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Browsing Specialized Clinical Programs and Services by Issue Date

Now showing items 1-20 of 412

Vitamin D3 dose requirement to raise 25-hydroxyvitamin D to desirable levels in adolescents: Results from a randomized controlled trial

Al-Shaar, Laila; Mneimneh, Rania; Nabulsi, Mona M.; Maalouf, Joyce; El-Hajj Fuleihan, Ghada A. (2014)

Several organizations issued recommendations on desirable serum 25-hydroxy vitamin D [25(OH)D] levels and doses of vitamin D needed to achieve them. Trials allowing the formulation of evidence-based recommendations in ...
Effect of natalizumab treatment on circulating plasmacytoid dendritic cells: A cross-sectional observational study in patients with multiple sclerosis

Kivisäkk, Pia; Francois, Katiana; Mbianda, Julvet; Gandhi, Roopali; Weiner, Howard L.; Khoury, Samia J. (Public Library of Science, 2014)

Objectives: Dendritic cells (DCs) serve a critical role both in promoting and inhibiting adaptive immunity. The goal of this study was to investigate the effect of natalizumab (NTZ) treatment on DC numbers, phenotype, and ...
Impact of changes in mortality on FRAX-derived fracture probabilities

Kreidieh, Omar I.; El-Hajj Fuleihan, Ghada A. (2014)

Background: Accurate hip fracture incidence and mortality rates are two essential requirements for FRAX calculators. Purpose: To investigate the effects of change in mortality on FRAX-derived fracture estimates. Methods: ...
Predicting falls using two instruments (the Hendrich Fall Risk Model and the Morse Fall Scale) in an acute care setting in Lebanon

Nassar, Nada; Helou, Nancy; Madi, Chantal (Blackwell Publishing Ltd, 2014)

Aims and objectives: To assess the predictive value of two instruments (the Morse Fall Scale (MFS) and the Heindrich II Fall Risk Model (HFRM)] in a Middle Eastern country (Lebanon) and to evaluate the factors that are ...
Hypovitaminosis D in a sunny country: Time trends, predictors, and implications for practice guidelines

Hoteit, M.; Al-Shaar, Laila; Yazbeck, Cynthia; Bou Sleiman, Maria; Ghalayini, Tala; El-Hajj Fuleihan, Ghada A. (W.B. Saunders, 2014)

The aim of the current study is to investigate the prevalence of hypovitaminosis D in Lebanese subjects, its robust predictors, evaluate the relationship between 25 hydroxy vitamin D [25(OH)D] and parathyroid hormone levels, ...
Consumer knowledge, attitudes and salt-related behavior in the Middle-East: The case of Lebanon

Nasreddine, Lara M.; Akl, Christelle; Al-Shaar, Laila; Almedawar, Mohamad Musbah; Isma’eel, Hussain A. (MDPI AG, 2014)

Sodium intake is high in Lebanon, a country of the Middle East region where rates of cardiovascular diseases are amongst the highest in the world. This study examines salt-related knowledge, attitude and self-reported ...
Lifetime cumulative exposure to waterpipe smoking is associated with coronary artery disease

Mehio-Sibai, Abla Mehio; Tohme, Rania A.; Almedawar, Mohamad Musbah; Itani, Taha; Yassine, Sara I.; Nohra, Eden A.; Isma’eel, Hussain A. (Elsevier Ireland Ltd, 2014)

Objective: Globally, waterpipe (WP) smoking is becoming a more prevalent form of tobacco consumption. Whilst research so far has demonstrated a significant link between WP use and a number of health outcomes, little is ...
The Nutrigenetics and Pharmacogenetics of Vitamin D Pathways

Awada, Zainab; Ossaily, Safaa; Khoueiry-Zgheib, Nathalie (Bentham Science Publishers B.V., 2014)

In this manuscript, we review the literature on the nutrigenetics and pharmacogenetics of vitamin D pathways, with a focus on genes involved in the pharmacokinetic and pharmacodynamic pathways of vitamin D as they have ...
Improved accuracy of anticoagulant dose prediction using a pharmacogenetic and artificial neural network-based method

Isma’eel, Hussain A.; Sakr, George E.; Habib, Robert H.; Almedawar, Mohamad Musbah; Khoueiry-Zgheib, Nathalie; Elhajj, Imad H. (2014)

Background: The unpredictability of acenocoumarol dose needed to achieve target blood thinning level remains a challenge. We aimed to apply and compare a pharmacogenetic least-squares model (LSM) and artificial neural ...
BCL6 controls Th9 cell development by repressing Il9 transcription

Bassil, Ribal; Orent, William; Olah, Marta; Kurdi, Ahmed T.; Frangieh, Michael; Buttrick, Thomas S.; Khoury, Samia J.; Elyaman, Wassim (American Association of Immunologists, 2014)

The transcriptional repressor B cell lymphoma 6 (BCL6) is required for the development of Th follicular cells, and it has been shown to suppress Th2 cell differentiation. We demonstrate that BCL6 is a key regulator of Th9 ...
The utilization of pre-implantation genetic testing in the absence of governance: A real-time experience

Farra, Chantal G.; Nassar, Anwar H.; Arawi, Thalia A.; Ashkar, Hanine; Monsef, Carla; Awwad, Johnny T. (Blackwell Publishing Ltd, 2014)

To create a diagnostic document describing the utilization of pre-implantation genetic testing (PGT) in the absence of monitoring and regulation. Retrospective cohort study of couples undergoing PGT between 2004 and 2007 ...
Increased late mortality after coronary artery bypass surgery complicated by isolated new-onset atrial fibrillation: a comprehensive propensity-matched analysis

Al-Shaar, Laila; Schwann, Thomas A.; Kabour, Ameer; Habib, Robert H. (Mosby Inc., 2014)

OBJECTIVES: The association of new-onset postoperative atrial fibrillation (POAF) and late death after coronary artery bypass grafting (CABG) has been confounded by the frequent concomitant serious complications that ...
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon

Mokhbat, Jacques Emile; Melhem, Nada Mohamad; El Khatib, Ziad Ziad; Zalloua, Pierre A. (Journal of Infection in Developing Countries, 2014)

Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. HIV-1 drug resistance (HIVDR) among ART-naive ...
Survival at the threshold of viability: A nationwide survey of the opinions and attitudes of physicians in a developing country

Charafeddine, Lama; Ammous, Farah; Kayle, Mariam I.; Arawi, Thalia A. (Blackwell Publishing Ltd, 2014)

Background To explore physicians' opinions and attitudes regarding resuscitation of extremely premature infants (EPIs) in a developing country with suboptimal resources. Methods A survey was developed, revised, and ...
The JOINT model of nurse absenteeism and turnover: A systematic review

Daouk-Öyry, Lina; Anouze, Abdel Latef; Otaki, Farah; Dumit, Nuhad Yazbik; Osman, Ibrahim H. (2014)

Background: Absenteeism and turnover among healthcare workers have a significant impact on overall healthcare system performance. The literature captures variables from different levels of measurement and analysis as being ...
ESO-ESMO 2nd international consensus guidelines for advanced breast cancer (ABC2)

Cardoso, Fatima V.; Costa, Alberto F.; Norton, Larry W.; Senkus, Elżbieta; Aapro, Matti S.; André, Fabrice; Barrios, Carlos Henrique Escosteguy; Bergh, Jonas C.S.; Biganzoli, Laura; Blackwell, Kimberly L.; Cardoso, Maria João; Čufer, Tanja; El-Saghir, Nagi S.; Fallowfield, Lesley J.; Fenech, Doris; Francis, Prudence A.; Gelmon, Karen A.; Giordano, Sharon Hermes; Gligorov, Joseph; Goldhirsch, Aaron; Harbeck, Nadia; Houssami, Nehmat; Hudis, Clifford A.; Kaufman, Bella; Krop, Ian E.; Kyriakides, Stella; Lin, U. N.; Mayer, Musa; Merjaver, Sofia D.; Nordström, Elizabeth Bergsten; Pagani, Olivia; Partridge, Ann Hart Md Mph; Pénault-Llorca, Fréd́erique M.; Piccart, Martine J.; Rugo, Hope S.; Sledge, George W.; Thomssen, Christoph; van't Veer, Laura J.; Vorobiof, Daniel Alberto; Vrieling, Conny; West, Nicola; Xu, Binghe; Winer, Eric P.Manuela (Elsevier Ltd, 2014)
Evaluation of circulating osteopontin levels in an unselected cohort of patients with multiple sclerosis: Relevance for biomarker development

Kivisäkk, Pia; Healy, Brian C.; Francois, Katiana; Gandhi, Roopali; Gholipour, Taha; Egorova, Svetlana S.; Sevdalinova, Velina; Quintana, Francisco J.; Chitnis, Tanuja; Weiner, Howard L.; Khoury, Samia J. (2014)

Background: Osteopontin (OPN) is a pleiotropic protein with important roles in inflammation and immunity that has been suggested as a candidate biomarker for disease activity in multiple sclerosis (MS). Objective: We ...
Primary carnitine deficiency: Novel mutations and insights into the cardiac phenotype

Shibbani, Kamel; Fahed, Akl C.; Al-Shaar, Laila; Arabi, Mariam Toufic; Nemer, Georges M.; Bitar, Fadi Fouad; Majdalani, Marianne Nimah (2014)

Solute carrier family 22 member 5 (SLC22A5) encodes a sodium-dependent ion transporter responsible for shuffling carnitine across the plasma membrane. This process provides energy for the heart, among other organs allowing ...
Outcome of breast cancer patients treated outside of clinical trials

El-Saghir, Nagi S.; Assi, Hussein A.; Jaber, Sara M.; Khoury, Katia E.; Nachef, Zahi; Mikdashi, Hana F.; El-Asmar, Nadine; Eid, Toufic A. (Ivyspring International Publisher, 2014)

Background: Information on outcome of breast cancer patients treated in the community is scarce. Data on outcome of patients treated in real-life clinical practice may provide useful information for performance improvement. ...
Estrogen receptor α is not a candidate gene for metabolic syndrome in Caucasian elderly subjects

Hoteit, M.; Arabi, Asma; Habib, Robert H.; Mahfouz, Rami A.R.; Baddoura, Rafic M.; Halaby, Georges H.; El-Hajj Fuleihan, Ghada A. (2014)

Objective Variants of estrogen receptor α (ERα) have been associated with obesity, dyslipidemia, diabetes and blood pressure. The Middle East registers some of the highest rate of metabolic syndrome worldwide. The aim of ...

Now showing items 1-20 of 412

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Browsing Specialized Clinical Programs and Services by Issue Date

Browsing Specialized Clinical Programs and Services by Issue Date

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