Collagenofibrotic glomerulopathy in a kidney transplant recipient: A first report
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Blackwell Publishing Ltd
Abstract
Collagenofibrotic glomerulopathy (CG) is a rare disease characterized by the deposition of collagen type 3 fibrils in the glomeruli. Patients may have proteinuria, hematuria, and/or renal dysfunction. CG is considered a progressive disease with variable rates of progression. The definitive diagnosis is made by electron microscopy with the presence of characteristic subendothelial and mesangial curved, comma-like, banded collagen type 3 fibers of 40–65 nm periodicity. We are reporting the first case of CG in a kidney transplant recipient with kidney disease of unknown cause. © 2020 The American Society of Transplantation and the American Society of Transplant Surgeons
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Keywords
Clinical research/practice, Genetics, Kidney transplantation/nephrology, Recurrent disease, Collagen type iii, Humans, Kidney diseases, Kidney glomerulus, Kidney transplantation, Proteinuria, Azathioprine, Calcineurin inhibitor, Collagen type 3, Collagen type 4, Creatinine, Cyclosporine, Dipeptidyl carboxypeptidase inhibitor, Mycophenolate mofetil, Prednisone, Tacrolimus, Adult, Albuminuria, Article, Capillary basement membrane, Case report, Clinical article, Collagen fiber, Collagen fibril, Collagenofibrotic glomerulopathy, Creatinine blood level, Cytoplasm, Diabetes mellitus, Drug substitution, Endothelium cell, Epithelium cell, Fibrosing alveolitis, Follow up, Glomerulopathy, Glomerulus capillary, Glucosuria, Graft recipient, Hematuria, Human, Hyaline degeneration, Hypertension, Immunohistochemistry, Immunosuppressive treatment, Iraqi, Kidney biopsy, Kidney cortex, Leg edema, Lymphocyte, Male, Mesangium, Microscopy, Plasma cell, Priority journal, Sclerosis, Adverse event, Glomerulus, Kidney disease