Diagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT)

Simple item page
dc.contributor.authorMohty, Mohamad
dc.contributor.authorMalard, Florent
dc.contributor.authorAlaskar, Ahmed S.
dc.contributor.authorAljurf, Mahmoud Deeb
dc.contributor.authorArat, Mutlu Ersöz
dc.contributor.authorBader, Peter
dc.contributor.authorBaron, Frédéric A.
dc.contributor.authorBazarbachi, Ali Abdul Hamid
dc.contributor.authorBlaise, Didier
dc.contributor.authorBrissot, Éolia
dc.contributor.authorCiceri, Fabio
dc.contributor.authorCorbacioglu, Selim
dc.contributor.authorDalle, Jean Hugues H.
dc.contributor.authorDignan, Fiona L.
dc.contributor.authorHuynh, Anne
dc.contributor.authorKenyon, Michelle
dc.contributor.authorNagler, Arnon
dc.contributor.authorPagliuca, Antonio
dc.contributor.authorPerić, Zinaida
dc.contributor.authorRichardson, Paul Gerard
dc.contributor.authorRuggeri, Annalisa
dc.contributor.authorRuutu, Tapani
dc.contributor.authorYakoub-Agha, Ibrahim
dc.contributor.authorDuarte, Rafael F.
dc.contributor.authorCarreras, Enric
dc.contributor.departmentInternal Medicine
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:45:54Z
dc.date.available2025-01-24T11:45:54Z
dc.date.issued2023
dc.description.abstractSinusoidal obstruction syndrome, also known as veno-occlusive disease (SOS/VOD), is a potentially life-threatening complication that can develop after hematopoietic cell transplantation (HCT). A new definition for diagnosis, and a severity grading system for SOS/VOD in adult patients, was reported a few years ago on behalf of the European Society for Blood and Marrow Transplantation (EBMT). The aim of this work is to update knowledge regarding diagnosis and severity assessment of SOS/VOD in adult patients, and also its pathophysiology and treatment. In particular, we now propose to refine the previous classification and distinguish probable, clinical and proven SOS/VOD at diagnosis. We also provide an accurate definition of multiorgan dysfunction (MOD) for SOS/VOD severity grading based on Sequential Organ Failure Assessment (SOFA) score. © 2023, The Author(s), under exclusive licence to Springer Nature Limited.
dc.identifier.doihttps://doi.org/10.1038/s41409-023-01992-8
dc.identifier.eid2-s2.0-85153340348
dc.identifier.pmid37095231
dc.identifier.urihttp://hdl.handle.net/10938/30611
dc.language.isoen
dc.publisherSpringer Nature
dc.relation.ispartofBone Marrow Transplantation
dc.sourceScopus
dc.subjectAdult
dc.subjectBone marrow
dc.subjectHematopoietic stem cell transplantation
dc.subjectHepatic veno-occlusive disease
dc.subjectHumans
dc.subjectSyndrome
dc.subjectVascular diseases
dc.subjectDefibrotide
dc.subjectUrsodeoxycholic acid
dc.subjectBone marrow transplantation
dc.subjectDisease severity
dc.subjectHuman
dc.subjectLiver venoocclusive disease
dc.subjectMedical society
dc.subjectMultiple organ failure
dc.subjectPathophysiology
dc.subjectProphylaxis
dc.subjectReview
dc.subjectRisk factor
dc.subjectSequential organ failure assessment score
dc.subjectLiver vein obstruction
dc.subjectVascular disease
dc.titleDiagnosis and severity criteria for sinusoidal obstruction syndrome/veno-occlusive disease in adult patients: a refined classification from the European society for blood and marrow transplantation (EBMT)
dc.typeReview

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
2023-602.pdf
Size:
743.92 KB
Format:
Adobe Portable Document Format
Download

Collections

Internal Medicine