Disseminated herpes simplex virus and varicella zoster virus co-infection in a patient with idiopathic thrombocytopenic purpura
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Elsevier Ltd
Abstract
Concomitant disseminated herpes simplex virus (HSV) and varicella zoster virus (VZV) infection is a rare event. We describe a case of disseminated HSV and VZV infection in an 80-year-old patient many years after splenectomy for idiopathic thrombocytopenic purpura (ITP). This is the first case of disseminated HSV-1 and VZV infection with molecular evidence of the simultaneous presence of both viruses in two different body sites (the skin and cerebrospinal fluid). This adds to the three reports of patients developing cutaneous disseminated herpes zoster multiple years after splenectomy for ITP. © 2018 The Authors
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Disseminated herpes simplex virus, Disseminated varicella zoster virus, Idiopathic thrombocytopenic purpura, Splenectomy, Aged, 80 and over, Coinfection, Diagnosis, differential, Fatal outcome, Female, Herpes simplex, Herpes zoster, Humans, Purpura, thrombocytopenic, idiopathic, Aciclovir, Ceftriaxone, Vancomycin, Aged, Article, Artificial ventilation, Case report, Cerebrospinal fluid, Clinical article, Computer assisted tomography, Emergency ward, Herpes simplex virus, Hospital admission, Human, Human alphaherpesvirus 1, Human cell, Human tissue, Intensive care unit, Lumbar puncture, Medical history, Mixed infection, Nonhuman, Postoperative complication, Priority journal, Skin biopsy, Surgical patient, Varicella zoster virus, Very elderly, Complication, Differential diagnosis, Fatality