Successful treatment of a solitary brain metastasis from small cell lung cancer with whole brain radiotherapy and stereotactic radiosurgery boost: A case report
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Blackwell Publishing Ltd
Abstract
Small cell lung cancer (SCLC) is an aggressive disease with a high potential for brain metastases. Treatment for metastatic SCLC is systemic chemotherapy, but the median overall survival remains poor. Cranial irradiation for palliative purposes using whole brain radiotherapy is the standard-of-care for patients with symptomatic brain metastases. However, few reports showed a prolonged survival in SCLC patients with solitary brain metastasis treated with a definitive intent. We report a case of a 62-year-old man who presented with solitary brain metastasis secondary to SCLC who was successfully treated with definitive radiotherapy to the primary lesion and the solitary brain metastasis, and followed up for 2 years. © 2018 The Authors. Precision Radiation Oncology published by John Wiley & Sons Australia, Ltd on behalf of Shandong Cancer Hospital & Institute.
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Metastasis, Prognosis, Radiotherapy, Small cell lung carcinoma, Bevacizumab, Cisplatin, Dexamethasone, Etoposide, Paracetamol, Adult, Article, Brain metastasis, Cancer combination chemotherapy, Case report, Chemoradiotherapy, Clinical article, Conformal radiotherapy, Coughing, Dysphagia, Dyspnea, Human, Male, Mediastinum mass, Middle aged, Multiple cycle treatment, Neuroendocrine tumor, Nuclear magnetic resonance imaging, Nuclear magnetic resonance spectroscopy, Occipital lobe, Odynophagia, Positron emission tomography-computed tomography, Priority journal, Radiation necrosis, Small cell lung cancer, Smoking, Stereotactic radiosurgery, Temporal lobe, Trachea compression, Tumor regression, Whole brain radiotherapy