Spinal intradural extramedullary granular cell tumor

Abstract

Background: Granular cell tumors (GCTs) are uncommon peripheral nerve sheath tumors of Schwann cell origin that may occur throughout the body. However, they rarely occur in the spinal canal. Case Description: A 49-year-old male presented with burning sensation in the left knee. The MRI of the lumbar spine showed an L3-L4 intradural extramedullary tumor. Complete surgical resection was successfully performed and the L3 root burning improved. Histopathologically, the lesion proved to be a benign GCT. Conclusion: Spinal GCTs are rare benign tumors that may be found in an intradural extramedullary location in the spine. The preferred treatment is complete surgical resection as subtotal/partial resection may result in recurrence warranting radiation therapy. © 2022 Published by Scientific Scholar on behalf of Surgical Neurology International.

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Keywords

Granular cell tumor, Intradural extramedullary, Intramedullary, Nerve sheath tumor, Spinal canal, Chlordane, Inhibin, Ki 67 antigen, Protein s 100, Transcription factor sox10, Adolescent, Adult, Aged, Anamnesis, Article, Burning sensation, Cancer surgery, Case report, Child, Clinical article, Contrast enhancement, Cytoplasm, Dissection, Eosinophil, Female, Fluoroscopy, Fourth lumbar vertebra, Histopathology, Human, Human cell, Human tissue, Immunohistochemistry, Intradural extramedullary granular cell tumor, Laminectomy, Lumbosacral spine, Male, Middle aged, Nerve root, Postoperative period, Proliferation index, School child, Soft tissue defect, Spinal root, T1 weighted imaging, T2 weighted imaging, Third lumbar vertebra, Transverse process, Treatment outcome, Tumor cell, Young adult

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