Principles of nanoparticle formation by flash nanoprecipitation

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dc.contributor.authorSaad, Walid S.
dc.contributor.authorPrud'Homme, Robert K.
dc.contributor.departmentDepartment of Chemical and Petroleum Engineering
dc.contributor.facultyMaroun Semaan Faculty of Engineering and Architecture (MSFEA)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:26:16Z
dc.date.available2025-01-24T11:26:16Z
dc.date.issued2016
dc.description.abstractRapid precipitation is an efficient approach for engineering materials at the nanoscale. By controlling solute nucleation and growth rates in solvent precipitation processes, the size of the resulting nanoparticles (NP) can be controlled. This review discusses Flash Nano precipitation (FNP), a technique developed for NP formation using copolymer stabilization. FNP has been explored for various applications, including NP formulation for drugs and imaging agents. The review highlights mixing considerations, supersaturation requirements, and stabilizer selection to provide controlled size NP via FNP, and includes a summary of current understanding of the FNP process, as well as relevant examples and applications. (C) 2016 Elsevier Ltd. All rights reserved.
dc.identifier.doihttps://doi.org/10.1016/j.nantod.2016.04.006
dc.identifier.eid2-s2.0-84992302753
dc.identifier.urihttp://hdl.handle.net/10938/26519
dc.language.isoen
dc.publisherElsevier B.V.
dc.relation.ispartofNano Today
dc.sourceScopus
dc.subjectFlash nanoprecipitation
dc.subjectNanoparticle
dc.subjectSupersaturation
dc.subjectBlock copolymer
dc.subjectDrug delivery
dc.subjectInlet vortex mixer
dc.subjectPolymeric nanoparticles
dc.subjectFluorescent nanoparticles
dc.subjectProtected nanoparticles
dc.subjectCurcumin nanoparticles
dc.subjectOral bioavailability
dc.subjectLipid nanoparticles
dc.subjectDrug nanoparticles
dc.subjectOrganic actives
dc.subjectJets mixer
dc.titlePrinciples of nanoparticle formation by flash nanoprecipitation
dc.typeReview

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