Malignant phyllodes tumor of the breast with spinal metastasis: Case report and review of literature

Abstract

Malignant phyllodes tumor is a rare neoplasm, usually detected on routine breast exams. Metastasis is unusual for this type of tumor and it mainly spreads via hematogenous routes. We present the case of a 54-year-old woman with thoracic spine metastasis of phyllodes tumor with osteosarcomatous differentiation 4 months following surgical resection of left breast mass. Malignant phyllodes tumors with osteosarcomatous differentiation are highly aggressive in nature and are unusual constituents of all breast cancers. Spinal metastasis of such tumor is rare and has been reported only among few cases in the literature. Surgical decompression with or without radiation is the best modality of treatment to relieve pain, regain neurological functions and prevent disease progression.