Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency
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W.B. Saunders
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Age of onset, Animals, Apoptosis, Autoimmune lymphoproliferative syndrome, Biopsy, Caspase 8, Colitis, ulcerative, Endoscopy, gastrointestinal, Epithelial cells, Genetic predisposition to disease, Heredity, Humans, Inflammasomes, Inflammation mediators, Intestines, Lymphocytes, Mice, knockout, Mutation, Phenotype, Actin, Azathioprine, Cd45ro antigen, Chemokine receptor ccr6, Chemokine receptor ccr7, Chemokine receptor cxcr3, Hla dr antigen, Infliximab, Interleukin 1beta, Interleukin 1beta converting enzyme, Lactate dehydrogenase, Steroid, Autacoid, Casp8 protein, human, Casp8 protein, mouse, Inflammasome, Animal experiment, Animal model, Anus disease, Article, Case report, Clinical article, Controlled study, Cytokine release, Diarrhea, Enteric feeding, Failure to thrive, Gene mutation, Germany, Hemicolectomy, Hospital patient, Human, Human tissue, Ileostomy, Immunity, Immunoblotting, Immunophenotyping, Inflammatory bowel disease, Nonhuman, Pancolitis, Peripheral blood mononuclear cell, Priority journal, Proctocolitis, Protein expression, T lymphocyte, Whole exome sequencing, Animal, Epithelium cell, Gastrointestinal endoscopy, Genetic predisposition, Genetics, Immunology, Intestine, Knockout mouse, Lymphocyte, Onset age, Pathology, Ulcerative colitis