Plasmacytoid dendritic cell depletion in DOCK8 deficiency: Rescue of severe herpetic infections with IFN-α 2b therapy
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Mosby Inc.
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Keywords
Antiviral agents, Child, Child, preschool, Dendritic cells, Female, Guanine nucleotide exchange factors, Herpesviridae infections, Homozygote, Humans, Immunophenotyping, Interferon-alpha, Mutation, Recombinant proteins, Severe combined immunodeficiency, Treatment outcome, Aciclovir, Dedicator of cytokinesis 8, Immunoglobulin, Peginterferon alpha2b, Protein derivative, Unclassified drug, Valaciclovir, Antibiotic agent, Case report, Disease severity, Herpes simplex, Human, Immune deficiency, Letter, Outcome assessment, Plasmacytoid dendritic cell, Preschool child, Priority journal, Treatment response, Absence of side effects, Antibiotic therapy, Antiviral therapy, Cellular immunodeficiency, Combined immunodeficiency, Dedicator of cytokinesis 8 deficiency, Dose response, Drug dose increase, Drug megadose, Ear disease, Ear ulceration, Exon, Gene deletion, Herpes labialis, Immunoprophylaxis, Infection prevention, Intron, Maintenance therapy, Plasmacytoid dendritic cell depletion, Remission, Subcutaneous immunotherapy, Suppurative otitis media, Topical treatment, Turk (people), Ulcer, Vesicular rash