Vitamin D Metabolism in Bariatric Surgery
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W.B. Saunders
Abstract
Hypovitaminosis D is common in obese patients and persists after roux-en-Y gastric bypass and sleeve gastrectomy. Several societies recommend screening for vitamin D deficiency before bariatric surgery, and replacement doses of 3000 IU/d and up to 50,000 IU 1 to 3 times per week, in case of deficiency, with periodic monitoring. These regimens are mostly based on expert opinion. Large trials are needed to assess the vitamin D dose response, by type of bariatric surgery, and evaluate the effect on surrogate markers of skeletal outcomes. Such data are essential to derive desirable vitamin D levels in this population. © 2017 Elsevier Inc.
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Keywords
Bariatric surgery, Guidelines, Obesity, Rygb, Sg, Vitamin d, Humans, Postoperative complications, Vitamin d deficiency, 25 hydroxyvitamin d, Calcitriol, Calcium, Colecalciferol, Ergocalciferol, Multivitamin, Parathyroid hormone, Placebo, 25-hydroxyvitamin d, Body mass, Bone density, Bone metabolism, Calcium blood level, Calcium urine level, Drug dose comparison, Drug dose increase, Fracture, Human, Loading drug dose, Malabsorption, Mineral metabolism, Morbid obesity, Osteomalacia, Priority journal, Review, Roux-en-y gastric bypass, Screening, Secondary hyperparathyroidism, Sleeve gastrectomy, Vitamin blood level, Vitamin d metabolism, Vitamin supplementation, Weight reduction, Analogs and derivatives, Blood, Postoperative complication