A young child with HIV and unsteady gait: A case report

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dc.contributor.authorYazbeck, Nadine H.
dc.contributor.authorYoussef, Yolla
dc.contributor.authorHanna-Wakim, Rima H.
dc.contributor.departmentPediatrics and Adolescent Medicine
dc.contributor.departmentSpecialized Clinical Programs and Services
dc.contributor.departmentCenter for Infectious Diseases Research
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T12:11:05Z
dc.date.available2025-01-24T12:11:05Z
dc.date.issued2020
dc.description.abstractBackground: We would like to raise awareness about the toxicities related to the added excipients present in the oral solution of Liponavir/ritonavir in particular alcohol and propylene glycol. Case presentation: In this case report, we describe an 18 month-old child with a newly diagnosed HIV infection on antiretroviral therapy (ART). She developed shortly after starting the ART unsteady gait and imbalance. Conclusions: The excipient-excipient interaction in Lopinavir/ritonavir may contribute to major toxicities not only in premature neonates and infants; but also in older children specifically from Asian ethnicity. © 2019 The Author(s)
dc.identifier.doihttps://doi.org/10.1016/j.idcr.2019.e00643
dc.identifier.eid2-s2.0-85076562085
dc.identifier.urihttp://hdl.handle.net/10938/32494
dc.language.isoen
dc.publisherElsevier Ltd
dc.relation.ispartofIDCases
dc.sourceScopus
dc.subjectHiv
dc.subjectLopinavir-ritonavir
dc.subjectUnsteady gait
dc.subjectAlanine aminotransferase
dc.subjectAspartate aminotransferase
dc.subjectLamivudine
dc.subjectLopinavir plus ritonavir
dc.subjectZidovudine
dc.subjectAbnormally high substrate concentration in blood
dc.subjectAcute hiv infection
dc.subjectAntiretroviral therapy
dc.subjectArticle
dc.subjectBody weight loss
dc.subjectCase report
dc.subjectCd4 lymphocyte count
dc.subjectChild
dc.subjectClinical article
dc.subjectDisease duration
dc.subjectDosing error
dc.subjectFemale
dc.subjectFever
dc.subjectHuman
dc.subjectLymphadenopathy
dc.subjectPriority journal
dc.subjectVirus load
dc.titleA young child with HIV and unsteady gait: A case report
dc.typeArticle

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