Radiation-Induced Fibrosis in Patients with Head and Neck Cancer: A Review of Pathogenesis and Clinical Outcomes
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SAGE Publications Ltd
Abstract
Radiotherapy-related fibrosis remains one of the most challenging treatment related side effects encountered by patients with head and neck cancer. Several established and ongoing novel therapies have been studied with paucity of data in how to best treat these patients. This review aims to provide researchers and health care providers with a comprehensive review on the presentation, etiology, and therapeutic options for this serious condition. © The Author(s) 2021.
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Keywords
Fibrosis, Head and neck radiation, Prevention, Radiotherapy, Clinical feature, Clinical outcome, Disease severity, Head and neck cancer, Human, Pathogenesis, Radiation fibrosis, Review, Risk factor