SuPAR, an emerging biomarker in kidney and inflammatory diseases

Simple item page
dc.contributor.authorHamie, Lamiaa
dc.contributor.authorDaoud, Georges E.
dc.contributor.authorNemer, Georges M.
dc.contributor.authorNammour, Tarek
dc.contributor.authorEl-Chediak, Alissar
dc.contributor.authorUthman, Imad W.
dc.contributor.authorKibbi, Abdul Ghani M.
dc.contributor.authorEid, Assaad A.
dc.contributor.authorKurban, Mazen S.
dc.contributor.departmentAnatomy, Cell Biology, and Physiological Sciences
dc.contributor.departmentBiochemistry and Molecular Genetics
dc.contributor.departmentInternal Medicine
dc.contributor.departmentDermatology
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:36:42Z
dc.date.available2025-01-24T11:36:42Z
dc.date.issued2018
dc.description.abstractSoluble urokinase plasminogen activator receptor (suPAR) is a circulating form of a physiological and pathophysiological important cell surface receptor, implicated in inflammation. Recent studies showed that suPAR is a promising biomarker, useful for diagnosis, assessment and prognosis of several diseases. This review summarises the majority of preliminary studies and analyses the significance and the clinical application of suPAR in various clinical conditions. SuPAR seems to have a significant value in the diagnosis as well as prognosis of many diseases; nonetheless, it merits large-scale studies to set cut-off values that help physicians in following up their patients and accordingly tailor their treatment plans. © Author(s) (or their employer(s)) 2018. No commercial re-use. See rights and permissions. Published by BMJ.
dc.identifier.doihttps://doi.org/10.1136/postgradmedj-2018-135839
dc.identifier.eid2-s2.0-85053138062
dc.identifier.pmid30177549
dc.identifier.urihttp://hdl.handle.net/10938/28695
dc.language.isoen
dc.publisherBMJ Publishing Group
dc.relation.ispartofPostgraduate Medical Journal
dc.sourceScopus
dc.subjectBiomarker
dc.subjectDiagnosis
dc.subjectInflammation
dc.subjectPrognosis
dc.subjectScreen
dc.subjectSoluble urokinase plasminogen activator receptor
dc.subjectBiomarkers
dc.subjectHumans
dc.subjectKidney diseases
dc.subjectReceptors, urokinase plasminogen activator
dc.subjectC reactive protein
dc.subjectPlasmin
dc.subjectPlasminogen
dc.subjectProcalcitonin
dc.subjectProteinase
dc.subjectUrokinase receptor
dc.subjectBiological marker
dc.subjectAcute myeloid leukemia
dc.subjectAcute pancreatitis
dc.subjectAtherosclerosis
dc.subjectDiabetes mellitus
dc.subjectDiabetic nephropathy
dc.subjectDisease severity
dc.subjectEnd stage renal disease
dc.subjectEstimated glomerular filtration rate
dc.subjectFocal glomerulosclerosis
dc.subjectGlomerulopathy
dc.subjectHuman
dc.subjectHuman immunodeficiency virus infection
dc.subjectImmunoglobulin a nephropathy
dc.subjectInflammatory disease
dc.subjectIntensive care unit
dc.subjectInterstitial nephritis
dc.subjectKidney disease
dc.subjectLiver cell carcinoma
dc.subjectLiver cirrhosis
dc.subjectLiver fibrosis
dc.subjectMembranous glomerulonephritis
dc.subjectMultiple myeloma
dc.subjectNon st segment elevation myocardial infarction
dc.subjectPeripheral occlusive artery disease
dc.subjectPlasmapheresis
dc.subjectProteinuria
dc.subjectPulmonary hypertension
dc.subjectRenin angiotensin aldosterone system
dc.subjectReview
dc.subjectRheumatoid arthritis
dc.subjectSepsis
dc.subjectSt segment elevation myocardial infarction
dc.subjectSystemic lupus erythematosus
dc.subjectSystemic sclerosis
dc.subjectBlood
dc.titleSuPAR, an emerging biomarker in kidney and inflammatory diseases
dc.typeReview

Files

Original bundle

Now showing 1 - 1 of 1
Thumbnail Image
Name:
2018-8014.pdf
Size:
2.01 MB
Format:
Adobe Portable Document Format
Download

Collections

Anatomy, Cell Biology, and Physiological Sciences
Biochemistry and Molecular Genetics
Dermatology
Internal Medicine