Abnormal subplate t2 hyperintensity involving the fetal brain in the second trimester: A heralding sign of polymicrogyria

Abstract

Fetal magnetic resonance imaging (MRI) has a high sensitivity and specificity in the diagnosis of cortical brain malformation in fetuses older than 24 weeks gestational age. As sensitivity of fetal MRI diminishes for younger fetuses, radiologist should be familiar with early cerebral signs appearing in the second trimester, heralding the formation of cortical brain malformation later in fetal life. We focus on polymicrogyria (PMG), we describe a case of unusual cystlike brain lesions in a 23 gestational weeks fetus that evolved toward polymicrogyria and we review all reported cases to date with early cerebral findings that evolved toward polymicrogyria. © 2018 Lebanese Order of Physicians.All right reserved.