Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma
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Cambridge University Press
Abstract
Objectives To report on the efficacy and adverse effects of interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma.Methods A retrospective chart review was conducted of eight patients with vocal process granuloma resistant to anti-reflux therapy who underwent interarytenoid botulinum toxin A injection. The mean dosage of botulinum toxin A injected was 6.56 U.Results Fifty per cent of patients had complete regression of the lesion and 50 per cent had partial regression. The main side effects were breathiness (n = 4), voice breaks (n = 1) and aspiration (n = 1).Conclusion Interarytenoid botulinum toxin A injection for the treatment of vocal process granuloma is an effective mode of therapy, with transient vocal and swallowing side effects. © Copyright JLO (1984) Limited, 2019.
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Keywords
Botulinum toxin, Granuloma, Injections, Voice, Adult, Aged, Botulinum toxins, type a, Female, Granuloma, laryngeal, Humans, Injections, intramuscular, Laryngeal muscles, Male, Middle aged, Neuromuscular agents, Retrospective studies, Treatment outcome, Vocal cords, Botulinum toxin a, Methylprednisolone, Muscle relaxant agent, Article, Aspiration, Clinical article, Drug efficacy, Follow up, Human, Larynx granuloma, Retrospective study, Side effect, Treatment response, Vocal process granuloma, Voice change, Intramuscular drug administration, Larynx muscle, Pathology, Vocal cord