Germline and somatic smoothened mutations in non-small-cell lung cancer are potentially responsive to hedgehog inhibitor vismodegib
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American Society of Clinical Oncology
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8 [4 (1 aminocyclobutyl)phenyl] 9 phenyl 1,2,4 triazolo[3,4 f][1,6]naphthyridin 3(2h) one, Cisplatin, Erlotinib, Etoposide, Smoothened protein, Vismodegib, Adult, Aged, Article, Basal cell carcinoma, Cancer radiotherapy, Case report, Child, Clinical article, Drug response, Exon, Female, Germline mutation, Histopathology, Human, Human cell, Human tissue, Lung adenocarcinoma, Lung biopsy, Male, Molecular diagnosis, Multiple cycle treatment, Non small cell lung cancer, Nonsmoker, Palliative therapy, Pedigree analysis, Preschool child, Priority journal, Smo gene, Somatic mutation, Squamous cell lung carcinoma