Acute toxoplasma dissemination with encephalitis in the era of biological therapies

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dc.contributor.authorGharamti, Amal A.
dc.contributor.authorRao, Amy
dc.contributor.authorPecen, Paula E.
dc.contributor.authorHenao-Martinez, Andres Felipe
dc.contributor.authorFranco-Paredes, Carlos
dc.contributor.authorMontoya, J. G.
dc.contributor.departmentInternal Medicine
dc.contributor.departmentDivision of Infectious Diseases
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:52:23Z
dc.date.available2025-01-24T11:52:23Z
dc.date.issued2018
dc.description.abstractWe report the case of a 65-year-old patient with pseudolymphoma who developed acute toxoplasmosis following 6 cycles of rituximab and bendamustine therapy. Acute toxoplasmosis in the setting of biological response modifiers, rather than reactivation, is a unique unreported infection. The patient developed severe disease with multi-organ involvement, including retinitis, myocarditis, and myositis. We discuss the clinical findings, epidemiology, and laboratory diagnosis. © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/
dc.identifier.doihttps://doi.org/10.1093/ofid/ofy259
dc.identifier.eid2-s2.0-85068074158
dc.identifier.urihttp://hdl.handle.net/10938/31056
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofOpen Forum Infectious Diseases
dc.sourceScopus
dc.subjectBiological therapy
dc.subjectEncephalitis
dc.subjectRituximab
dc.subjectToxoplasma gondii
dc.subjectToxoplasmosis
dc.subjectWild boar
dc.subjectAbatacept
dc.subjectBendamustine
dc.subjectCotrimoxazole
dc.subjectImmunoglobulin g
dc.subjectImmunoglobulin m
dc.subjectTrametinib
dc.subjectAdult
dc.subjectArticle
dc.subjectCase report
dc.subjectCell proliferation
dc.subjectCerebrospinal fluid analysis
dc.subjectClinical article
dc.subjectDyspnea
dc.subjectEchocardiography
dc.subjectEnzyme linked immunosorbent assay
dc.subjectEye examination
dc.subjectEye swelling
dc.subjectHuman
dc.subjectLeg pain
dc.subjectMale
dc.subjectMiddle aged
dc.subjectMultiple cycle treatment
dc.subjectMyocarditis
dc.subjectMyositis
dc.subjectNuclear magnetic resonance imaging
dc.subjectPleocytosis
dc.subjectPolymerase chain reaction
dc.subjectPriority journal
dc.subjectPseudolymphoma
dc.subjectRadiation dose
dc.subjectRetinitis
dc.subjectRheumatoid arthritis
dc.titleAcute toxoplasma dissemination with encephalitis in the era of biological therapies
dc.typeArticle

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