A glimpse into the history of description of the antiphospholipid syndrome
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SAGE Publications Ltd
Abstract
Prior to 1983, several landmark reports prepared the stage for a detailed description of the Antiphospholipid (Hughes) syndrome (APS). Formerly depicted as lupus-like, APS exhibits a wide spectrum of symptoms that overlap with Sjogren’s, Hashimoto, and other autoimmune diseases. In this review, we take a glimpse into the history of description of APS, discussing the events that led to its recognition as one of the most common autoimmune diseases and the enormous impact of that recognition in the rheumatology field. © The Author(s) 2020.
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Keywords
Abortion, Anticardiolipin, Anticoagulation, Antiphospholipid antibodies, Antiphospholipid syndrome, Beta 2 glycoprotein i, History, Hughes syndrome, Lupus anticoagulant, Thrombosis, Abortion, habitual, Antibodies, anticardiolipin, Beta 2-glycoprotein i, Female, History, 20th century, Humans, Lupus coagulation inhibitor, Pregnancy, Pregnancy complications, hematologic, Beta2 glycoprotein 1, Plasma protein, Cardiolipin antibody, Autoimmune disease, False positive result, Fetus wastage, History of medicine, Human, Laboratory test, Pregnancy disorder, Priority journal, Review, Rheumatology, Blood, Classification, Immunology, Pathology, Pregnancy complication, Recurrent abortion