Ovarian teratoma: Yet another cause of immune thrombocytopenia
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Dove Medical Press Ltd
Abstract
A hematologic disorder occurred simultaneously with an ovarian cystic teratoma in a young woman. The blood disorder was a severe thrombocytopenia, with no spontaneous remission, or improvement after steroids tapering. To date, this is the second report in literature of immune thrombocytopenia associated with an ovarian teratoma, completely resolving following surgical excision of the ovarian teratoma. This case may suggest a potential peptide secreted by the ovarian teratoma toxic to platelets, and or a genetic predisposition in patients displaying the syndrome. Further research is needed in this area to highlight the mechanism of association. © 2018 Khalife et al.
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Immune thrombocytopenia purpura, Laparoscopic surgery, Mature ovarian teratoma, Esterase, Prednisone, Abdominal pain, Abdominal tenderness, Adnexa disease, Adult, Article, Ascites, Blood analysis, Blood pressure, Case report, Clinical article, Computer assisted tomography, Coombs test, Corpus luteum, Cystectomy, Disease association, Dizziness, Emergency ward, Erythrocyte transfusion, Female, Gynecologic care, Headache, Heart rate, Hemoperitoneum, Histopathology, Human, Human tissue, Idiopathic thrombocytopenic purpura, Iron deficiency anemia, Medical history, Neuralgia, Nulligravida, Ovary teratoma, Petechia, Platelet count, Preoperative care, Saliva analysis, Steroid therapy, Tachycardia, Urinalysis