Henoch-Schönlein purpura: Another COVID-19 complication
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John Wiley and Sons Inc
Abstract
Whether affecting children or adults, SARS-CoV-2 infection (COVID-19) can have multi-organ involvement mediated by an inflammatory cascade. Immunoglobulin A (IgA) is one of the key components of the inflammatory cascade that can lead to endothelial injury and inflammation. IgA vasculitis or Henoch-Schönlein purpura (HSP) has been rarely reported in the context of COVID-19. In this report, we highlight a case of HSP occurring 2 days after diagnosis of COVID-19 in a 16-year-old boy, who presented with palpable purpura of the lower extremities and buttocks, diffuse abdominal pain, hemoptysis, and hematochezia. He was treated with oral prednisolone with rapid clinical improvement. © 2021 Wiley Periodicals LLC.
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Keywords
Covid-19, Henoch-schönlein purpura, Immunomodulation, Vasculitides, Adolescent, Child, Humans, Male, Pain, Prednisolone, Purpura, schoenlein-henoch, Sars-cov-2, Cotrimoxazole, Immunoglobulin a, Ramipril, Abdominal pain, Anaphylactoid purpura, Article, Body surface, Buttock, Case report, Clinical article, Coronavirus disease 2019, Disease duration, Disease severity, Hematuria, Hemoptysis, Hospital discharge, Human, Hypoalbuminemia, Immunoglobulin blood level, Immunoglobulin deficiency, Knee, Lower limb, Myalgia, Patient isolation, Proteinuria, Purpuric rash, Rectum hemorrhage, Sore throat, Urinalysis, Complication