Successful Thrombolysis in the Setting of Marfan Syndrome and Chronic Aortic Dissection
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Lippincott Williams and Wilkins
Abstract
Introduction:Thrombolysis is the standard of care in acute ischemic stroke. It is usually contraindicated in patients with aortic dissection.Case Report:We report a case of Marfan syndrome and chronic aortic dissection presenting with acute ischemic stroke treated with thrombolysis.Conclusion:To our knowledge, this is the first case of Marfan syndrome with chronic aortic dissection undergoing thrombolysis for acute ischemic stroke with a near-complete recovery of neurological deficit and favorable long-term outcome. © 2019 Lippincott Williams and Wilkins. All rights reserved.
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Aortic dissection, Ischemic stroke, Marfan syndrome, Thrombolysis, Adult, Aneurysm, dissecting, Brain ischemia, Fibrinolytic agents, Humans, Male, Stroke, Thrombolytic therapy, Tissue plasminogen activator, Treatment outcome, Alteplase, Anticoagulant agent, Warfarin, Fibrinolytic agent, Anticoagulant therapy, Aortic valve replacement, Article, Ascending aorta, Blood clot lysis, Case report, Cerebral artery disease, Clinical article, Clinical examination, Computed tomographic angiography, Computer assisted tomography, Dysarthria, Facial weakness, Follow up, Gaze, Hospital admission, Human, Human cell, Hypertension, Lacunar stroke, Lens subluxation, Medical history, Neuroimaging, Priority journal, Slurred speech, Vitrectomy, Weakness, Cerebrovascular accident, Complication, Dissecting aneurysm, Fibrinolytic therapy