Successful Thrombolysis in the Setting of Marfan Syndrome and Chronic Aortic Dissection

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dc.contributor.authorMalek, Elia Gebran
dc.contributor.authorNasreddine, Wassim M.
dc.contributor.authorMakki, Achraf
dc.contributor.departmentNeurology
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T12:07:35Z
dc.date.available2025-01-24T12:07:35Z
dc.date.issued2019
dc.description.abstractIntroduction:Thrombolysis is the standard of care in acute ischemic stroke. It is usually contraindicated in patients with aortic dissection.Case Report:We report a case of Marfan syndrome and chronic aortic dissection presenting with acute ischemic stroke treated with thrombolysis.Conclusion:To our knowledge, this is the first case of Marfan syndrome with chronic aortic dissection undergoing thrombolysis for acute ischemic stroke with a near-complete recovery of neurological deficit and favorable long-term outcome. © 2019 Lippincott Williams and Wilkins. All rights reserved.
dc.identifier.doihttps://doi.org/10.1097/NRL.0000000000000251
dc.identifier.eid2-s2.0-85074550524
dc.identifier.pmid31688710
dc.identifier.urihttp://hdl.handle.net/10938/31571
dc.language.isoen
dc.publisherLippincott Williams and Wilkins
dc.relation.ispartofNeurologist
dc.sourceScopus
dc.subjectAortic dissection
dc.subjectIschemic stroke
dc.subjectMarfan syndrome
dc.subjectThrombolysis
dc.subjectAdult
dc.subjectAneurysm, dissecting
dc.subjectBrain ischemia
dc.subjectFibrinolytic agents
dc.subjectHumans
dc.subjectMale
dc.subjectStroke
dc.subjectThrombolytic therapy
dc.subjectTissue plasminogen activator
dc.subjectTreatment outcome
dc.subjectAlteplase
dc.subjectAnticoagulant agent
dc.subjectWarfarin
dc.subjectFibrinolytic agent
dc.subjectAnticoagulant therapy
dc.subjectAortic valve replacement
dc.subjectArticle
dc.subjectAscending aorta
dc.subjectBlood clot lysis
dc.subjectCase report
dc.subjectCerebral artery disease
dc.subjectClinical article
dc.subjectClinical examination
dc.subjectComputed tomographic angiography
dc.subjectComputer assisted tomography
dc.subjectDysarthria
dc.subjectFacial weakness
dc.subjectFollow up
dc.subjectGaze
dc.subjectHospital admission
dc.subjectHuman
dc.subjectHuman cell
dc.subjectHypertension
dc.subjectLacunar stroke
dc.subjectLens subluxation
dc.subjectMedical history
dc.subjectNeuroimaging
dc.subjectPriority journal
dc.subjectSlurred speech
dc.subjectVitrectomy
dc.subjectWeakness
dc.subjectCerebrovascular accident
dc.subjectComplication
dc.subjectDissecting aneurysm
dc.subjectFibrinolytic therapy
dc.titleSuccessful Thrombolysis in the Setting of Marfan Syndrome and Chronic Aortic Dissection
dc.typeArticle

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