Investigating the Effects of Exposure to Waterpipe Smoke on Pregnancy Outcomes Using an Animal Model

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dc.contributor.authorKhabour, Omar Falah
dc.contributor.authorAlzoubi, Karem Hasan
dc.contributor.authorAl-Sheyab, Nihaya A.
dc.contributor.authorShihadeh, Alan Louis
dc.contributor.authorEissenberg, Thomas E.
dc.contributor.departmentDepartment of Mechanical Engineering
dc.contributor.facultyMaroun Semaan Faculty of Engineering and Architecture (MSFEA)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:32:08Z
dc.date.available2025-01-24T11:32:08Z
dc.date.issued2016
dc.description.abstractIntroduction: In recent years, waterpipe tobacco smoking has been increasing in popularity all over the world. In this study, we explored effects of waterpipe smoking on pregnancy outcomes in rats. Methods: Animals were exposed to waterpipe tobacco smoking using a whole body exposure system 2 hours per day during pregnancy. A control group was exposed to fresh air only. Results: The results showed significant association between exposure to waterpipe smoke during pregnancy and low birth weight (P < .01) and neonatal death (P < .01). In addition, the rate of growth of offspring of the waterpipe group was significantly lower than that of control group as measured by body weight gain during the first 3 months of life (P < .001). No effect was found for waterpipe smoking on mean number of progeny and male to female ratio among offspring. Conclusion: Waterpipe smoking is associated with adverse effects on pregnancy outcomes. Implications: In this study, we investigated for the first time the effect of waterpipe smoking on pregnancy outcomes using animal model. The results clearly showed that waterpipe smoking is associated with adverse effects on pregnancy outcomes that include low birth weigh, neonatal survival, and growth retardation. © The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved.
dc.identifier.doihttps://doi.org/10.1093/ntr/ntv275
dc.identifier.eid2-s2.0-84964939408
dc.identifier.pmid26681774
dc.identifier.urihttp://hdl.handle.net/10938/27704
dc.language.isoen
dc.publisherOxford University Press
dc.relation.ispartofNicotine and Tobacco Research
dc.sourceScopus
dc.subjectAnimals
dc.subjectDisease models, animal
dc.subjectFemale
dc.subjectInfant, low birth weight
dc.subjectPregnancy
dc.subjectPregnancy outcome
dc.subjectRats
dc.subjectSmoking
dc.subjectWeight gain
dc.subjectAdverse outcome
dc.subjectAnimal experiment
dc.subjectArticle
dc.subjectBody weight
dc.subjectControlled study
dc.subjectGrowth rate
dc.subjectGrowth retardation
dc.subjectLow birth weight
dc.subjectNewborn death
dc.subjectNonhuman
dc.subjectPriority journal
dc.subjectProgeny
dc.subjectRat
dc.subjectSex ratio
dc.subjectSmoking cessation program
dc.subjectSmoking regulation
dc.subjectWaterpipe smoking
dc.subjectAdverse effects
dc.subjectAnimal
dc.subjectDisease model
dc.subjectDrug effects
dc.titleInvestigating the Effects of Exposure to Waterpipe Smoke on Pregnancy Outcomes Using an Animal Model
dc.typeArticle

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