The societal costs of multiple sclerosis in Lebanon: a cross-sectional study

Abstract

Introduction: This study assessed the societal costs of multiple sclerosis (MS) in Lebanon, categorized by disease severity. Methods: This was a cross-sectional, prevalence-based, bottom-up study using a face-to-face questionnaire. Patients were stratified by disease severity using the expanded disability status scale (EDSS); EDSS scores of 0–3, 4–6.5, and 7–9 indicating respectively mild, moderate, and severe MS. All direct medical, nonmedical, and indirect costs related to reduced productivity were accounted for regardless of who bore them. Costs, collected from various sources, were presented in international US dollars (US$) using the purchasing power parity (PPP) conversion rate. Results: We included 210 Lebanese patients (mean age: 43.3 years; 65.7% females). The total annual costs per patient were PPP US$ 33,117 for 2021, 12.4 times higher than the nominal GDP per capita. Direct costs represented 52% (US$ 17,185), direct nonmedical costs 8% (US$ 2,722), and indirect costs 40% (US$ 13, 211) of the mean annual costs. The total annual costs per patient increased with disease severity and were PPP US$ 29,979, PPP US$ 36,125, PPP US$ 39,136 for mild, moderate, and severe MS, respectively. Conclusion: This study reveals the huge economic burden of MS on the Lebanese healthcare system and society. © 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

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Keywords

Cost-of-illness, Economic burden, Healthcare consumption, Lebanon, Multiple sclerosis, Productivity losses, Adult, Cost of illness, Cross-sectional studies, Female, Health care costs, Humans, Male, Quality of life, Severity of illness index, Surveys and questionnaires, Alemtuzumab, Alpha tocopherol, Beta1a interferon, Cladribine, Dimethyl fumarate, Fingolimod, Gylenia, Natalizumab, Ocrelizumab, Omega 3 fatty acid, Peginterferon beta1a, Rituximab, Sclemod, Selenium, Teriflunomide, Vitamin b group, Vitamin d, Aged, Article, Cross-sectional study, Disease severity, Economic crisis, Expanded disability status scale, Gross national product, Health care cost, Human, Major clinical study, Productivity, Purchasing power, Societal cost, Questionnaire

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