Outcomes of cirrhotic patients admitted to the intensive care unit after a successful cardiac arrest resuscitation

Abstract

Objectives: To evaluate the outcomes of cirrhotic patients admitted to the intensive care unit)ICU(following cardiac arrest. Methods: This was a single centre retrospective study of all the cirrhotic patients, admitted to the ICU at King Abdulaziz Medical City, Riyadh, Saudi Arabia, after a successful cardiac arrest resuscitation, from 1999 to 2017. The characteristics of the hospital survivors and non-survivors were compared. Results: A total of 76 patients were admitted to the ICU during the study period, with a median age of 64 years. In addition to cirrhosis, the patients had other chronic comorbidities, including chronic renal disease)32.9%(and diabetes)47%(. Of this group, 67)88.2%(died in the hospital, and 54)71%(died while in ICU. Compared to the group who survived, all non-survivors required mechanical ventilation and had a higher median APACHE II score of 38)p=0.006(, a lower median Glasgow coma score)GCS(of 3)p=0.0003(, and a higher median lactic acid of 6.4 mmol/L)p=0.032(. On multivariable logistic regression analysis, the important predictors of hospital mortality were APACHE II score)p=0.006(, bilirubin level)p=0.008(and GCS)p=0.005(. Conclusion: Cirrhotic patients admitted to the ICU following cardiac arrest have high mortality. Patients with higher APACHE II scores, higher bilirubin and lower GCS have higher risk of in-hospital mortality. © 2021 Saudi Arabian Armed Forces Hospital. All rights reserved.