Sleepiness and Health-Related Quality of Life Among Kidney Transplant Recipients in a Low-Middle Income Country: A Cross-Sectional Study

Abstract

This study aims to describe daytime sleepiness and health-related quality of life (HRQoL) among Lebanese kidney transplant (KT) recipients and to examine the medical, psychosocial and transplant factors related to them. It is a cross-sectional multi-center study involving KT recipients >18 years. Daytime sleepiness was assessed using ESS Questionnaire. HRQoL was measured using the SF-36 questionnaire. Social support was self-reported. A multivariable regression analysis evaluated factors associated with daytime sleepiness and HRQoL in our sample. 118 patients were recruited over a 2 years period. Excessive daytime sleepiness was prevalent in 12.7%. It was associated with Diabetes Mellitus (OR 3.97, 95% CI 0.94–16.81, p = 0.06) and obesity (OR 1.13, 95% CI 1.02, 1.27, p = 0.02). Social support and higher eGFR were associated with better scores on the MCS (β 24.13 p < 0.001 and β 0.26 p < 0.01) and the PCS (β 15.48 p < 0.01 and β 0.22 P 0.02). Conversely, depression and hospitalization were negatively associated with the MCS (β −27.44, p < 0.01 and β −9.87, p < 0.01) and the PCS (β −0.28.49, p < 0.01 and β −10.37, p < 0.01). Copyright © 2023 Hoteit, Al-Masry, Elbejjani, Aoun, Abu-Dargham, Medawar, Abou Zeinab, Farhood and Koubar.

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Keywords

Kidney transplant, Low-middle income, bmi, Quality of life, Sleepiness, Social support, Cross-sectional studies, Developing countries, Disorders of excessive somnolence, Humans, Kidney transplantation, Surveys and questionnaires, Azathioprine, Creatinine, Cyclosporine, Everolimus, Prednisone, Sirolimus, Tacrolimus, Adult, Alcohol consumption, Article, Autoimmune disease, Daytime somnolence, Delayed graft function, Dyslipidemia, Epworth sleepiness scale, Estimated glomerular filtration rate, Female, Generalized anxiety disorder-7, Graft recipient, Hospitalization, Human, Hypertension, Kidney graft, Low income country, Major clinical study, Male, Malignant neoplasm, Mental health, Middle income country, Multivariate logistic regression analysis, Pain, Patient health questionnaire 9, Questionnaire, Short form 36, Social interaction, Somnolence, Clinical trial, Cross-sectional study, Developed country, Multicenter study, Psychology

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