Treatment of multiple sclerosis in special populations: The case of refugees

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SAGE Publications Inc.

Abstract

Multiple sclerosis was long considered a relatively rare entity in the Middle East, but research over the past 10 years and the publication of the Middle East North Africa Committee for Treatment and Research in Multiple Sclerosis guidelines for multiple sclerosis have allowed diagnosis and treatment to occur more efficiently. Most of the first and second-line disease-modifying therapies approved by the Food and Drug Administration and the European Medicine Agency are available in the Middle East. However, the availability of disease-modifying therapies is quite variable, with some countries having access to all multiple sclerosis disease-modifying therapies, while in others there is only one therapeutic option. Economic limitations remain a challenge for the management of multiple sclerosis, especially in countries of war. Moreover, the burden of multiple sclerosis treatment in Syrian and Palestinian refugees is likely high due to the non-availability of funds to cover the high cost of disease-modifying therapies. © The Author(s) 2020.

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Middle east, Multiple sclerosis, Palestinian, Refugees, Syrian, Treatment, Alemtuzumab, Azathioprine, Cladribine, Cyclophosphamide, Fingolimod, Fumaric acid dimethyl ester, Glatiramer, Interferon beta serine, Methotrexate, Mitoxantrone, Mycophenolate mofetil, Natalizumab, Ocrelizumab, Rituximab, Teriflunomide, Algorithm, Article, Cost effectiveness analysis, Drug bioavailability, Drug cost, Economic evaluation, Food and drug administration, Hospitalization, Human, Immunosuppressive treatment, Incidence, Myelooptic neuropathy, Non-governmental organization, Off label drug use, Personalized medicine, Population, Prevalence, Primary medical care, Priority journal, Protocol compliance, Public health, Publication, Refugee, Vaccination

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