Autonomic dysfunction in idiopathic hypersomnia: An overlooked association and potential management
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American Academy of Sleep Medicine
Abstract
There is a small yet robust body of literature regarding autonomic dysfunction in idiopathic hypersomnia as well as sleep disturbances in postural orthostatic tachycardia syndrome. This review aims at summarizing the current literature and highlighting gaps in the current knowledge. This article additionally presents the personal experience of one of the authors at the sleep center. © 2022 American Academy of Sleep Medicine. All rights reserved.
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Keywords
Autonomic dysfunction, Excessive daytime sleepiness, Idiopathic hypersomnia, Postural orthostatic tachycardia syndrome, Disorders of excessive somnolence, Humans, Sleep, Acetylcholine, Amphetamine plus dexamphetamine, Immunoglobulin, Muscarinic receptor, Adult, Article, Autonomic nervous system function, Autonomic reflex, Case report, Clinical article, Daytime somnolence, Disease association, Female, Head-up tilt test, Heart preload, Heart rate variability, Human, Hyperpnea, Immune dysregulation, Immunotherapy, Medical history, Orthostatic hypotension, Polysomnography, Pressoreceptor reflex, Rem sleep, Sleep latency, Stomach emptying, Stomach paresis, Treatment outcome, Valsalva maneuver, Complication, Somnolence