Nondepolarizing muscle relaxant improves direct laryngoscopy view with no effect on face mask ventilation

dc.contributor.authorRizk, Marwan Sarkis
dc.contributor.authorZeineldine, Salah M.
dc.contributor.authorEl-Khatib, Mohamad Farouk
dc.contributor.authorYazbeck-Karam, V. G.
dc.contributor.authorAyoub, Sophie D.
dc.contributor.authorBou-Khalil, Pierre
dc.contributor.authorAbi-Nader, Elie
dc.contributor.authorGhabach, Marc M.
dc.contributor.authorAyoub, Chakib Maurice
dc.contributor.departmentDepartment of Biology
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.facultyFaculty of Arts and Sciences (FAS)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:20:41Z
dc.date.available2025-01-24T11:20:41Z
dc.date.issued2017
dc.description.abstractBackground Difficult or impossible face mask ventilation complicated with difficult tracheal intubation during anesthesia induction occurs in 0.4% of adult anesthesia cases, possibly leading to life‐threatening complications. Because of such catastrophes, muscle relaxants have been recommended to be administered after confirming adequate face mask ventilation without a solid scientific validation of this principal. Methods In this observational study, the ease of ventilation and the scores of direct laryngoscopy views before and after administration of cisatracurium were assessed in ninety young healthy adults, without anesthetic risks and without foreseen difficult intubation and who were scheduled for general elective surgeries. Results Before muscle relaxation, 43 patients (48%) were Cormack Grade I, while the remaining 47 patients (52%) were either Cormack Grade II (28 patients, 31%) or Cormack Grade II (19 patients, 21%). Following muscle relaxation with cisatracurium, the number of patients with Cormack Grade I significantly increased from 43 patients (48%) to 65 patients (72%) (p = 0.0013). Only 1 patient out of 19 patients (5%) improved his Cormack grade from Grade III to Grade I while 16 out 19 patients (84%) improved their Cormack grade from Grade III to Grade II after the use of cisatracurium. The quality of face mask ventilation did not differ with and without muscle relaxants in all patients. Conclusion The use of cisatracurium in healthy young adults undergoing general elective surgeries with no anticipated difficult endotracheal intubation had no effect on the quality of face mask ventilation despite resulting in a quantifiable improvement in the laryngeal view. © 2017
dc.identifier.doihttps://doi.org/10.1016/j.bjan.2016.07.006
dc.identifier.urihttp://hdl.handle.net/10938/25095
dc.language.isoen
dc.publisherElsevier Editora Ltda
dc.sourceScopus
dc.subjectFace mask ventilation
dc.subjectLaryngoscopy view
dc.subjectNondepolarizing muscle relaxants
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAnesthesia
dc.subjectFemale
dc.subjectHumans
dc.subjectLaryngoscopy
dc.subjectMale
dc.subjectMiddle aged
dc.subjectNeuromuscular nondepolarizing agents
dc.subjectProspective studies
dc.subjectYoung adult
dc.subjectCisatracurium
dc.subjectNeuromuscular blocking agent
dc.subjectArticle
dc.subjectArtificial ventilation
dc.subjectElective surgery
dc.subjectEndotracheal intubation
dc.subjectFace mask
dc.subjectHuman
dc.subjectMajor clinical study
dc.subjectMuscle relaxation
dc.subjectObservational study
dc.subjectProcedures
dc.subjectProspective study
dc.titleNondepolarizing muscle relaxant improves direct laryngoscopy view with no effect on face mask ventilation
dc.typeArticle

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