Challenges Facing Viral Hepatitis C Elimination in Lebanon
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Abstract
Hepatitis C is a hepatotropic virus that causes progressive liver inflammation, eventually leading to cirrhosis and hepatocellular carcinoma if left untreated. All infected patients can achieve a cure if treated early. Unfortunately, many patients remain asymptomatic and tend to present late with hepatic complications. Given the economic and health burdens of chronic hepatitis C infection, the World Health Organization (WHO) has proposed a strategy to eliminate hepatitis C by 2030. This article describes the epidemiology of hepatitis C in Lebanon and highlights the challenges hindering its elimination. An extensive search was conducted using PubMed, Medline, Cochrane, and the Lebanese Ministry of Public Health–Epidemiologic Surveillance Unit website. Obtained data were analyzed and discussed in light of the current WHO recommendations. It was found that Lebanon has a low prevalence of hepatitis C. Incidence is higher among males and Mount Lebanon residents. A wide variety of hepatitis C genotypes exists among various risk groups, with genotype 1 being the most predominant. In Lebanon, many barriers prevent successful hepatitis C elimination, including the absence of a comprehensive screening policy, stigma, neglect among high-risk groups, economic collapse, and a lack of proper care and surveillance among the refugees. Appropriate screening schemes and early linkage to care among the general and high-risk populations are essential for successful hepatitis C elimination in Lebanon. © 2023 by the authors.
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Challenges, Elimination, Hepatitis c, Incidence, Infection, Lebanon, Prevalence, Nonstructural protein 5a, Peginterferon, Ribavirin, Acquired immune deficiency syndrome, Antiviral therapy, Blood transfusion, Cd4 lymphocyte count, Chronic hepatitis, Chronic hepatitis c, Disease transmission, Genetic association, Genetic variability, Hemodialysis, Hepatic encephalopathy, Hepatitis c virus, High risk population, Human, Inflammation, Kidney transplantation, Lebanese, Length of stay, Liver cirrhosis, Liver fibrosis, Peritoneal dialysis, Public health, Quality of life, Review, Risk factor, Secondary prevention, Seroprevalence, Sustained virologic response, Systematic review, Vaccination, Vaccinia virus, Virus load, Virus replication, Virus transmission, Wart virus, World health organization