Challenges in the treatment of acute fulminant hepatitis B: Case report and literature review

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dc.contributor.authorAlawieh, Ali Mostafa
dc.contributor.authorEldine, Rakan Nasser
dc.contributor.authorYoussef, Mona M.
dc.contributor.authorBizri, Abdul Rahman N.
dc.contributor.departmentInternal Medicine
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T11:46:21Z
dc.date.available2025-01-24T11:46:21Z
dc.date.issued2015
dc.description.abstractAcute hepatitis B is a serious cause of fulminant hepatic failure and subsequent mortality. No established guidelines are currently present for the treatment of this life threatening entity. Several therapeutic options were reported in the literature including the use of lamivudine as well as the more novel nucleoside analogue entecavir. We report an unfortunate case of fulminant hepatitis B that passed away despite intensive care unit management and treatment with entecavir in combination with steroids. Extensive review of the literature about various therapeutic approaches to manage fulminant hepatitis B was conducted. The aim of this report is to emphasize the need for larger more structured studies in order to improve the outcome of the treatment of this entity. © 2015, Lebanese Order of Physicians. All rights reserved.
dc.identifier.doihttps://doi.org/10.12816/0012559
dc.identifier.eid2-s2.0-84938560296
dc.identifier.pmid26164980
dc.identifier.urihttp://hdl.handle.net/10938/30651
dc.language.isoen
dc.publisherLebanese Order of Physicians
dc.relation.ispartofJournal Medical Libanais
dc.sourceScopus
dc.subjectAcute hepatitis b
dc.subjectEntecavir
dc.subjectFulminant hepatic failure
dc.subjectFulminant hepatitis b
dc.subjectLamivudine
dc.subjectAntiviral agents
dc.subjectFatal outcome
dc.subjectGuanine
dc.subjectHepatitis b
dc.subjectHumans
dc.subjectLiver failure, acute
dc.subjectMale
dc.subjectMiddle aged
dc.subjectAnticonvulsive agent
dc.subjectSteroid
dc.subjectAntivirus agent
dc.subjectAbdominal pain
dc.subjectAcute pancreatitis
dc.subjectAdult
dc.subjectAntiviral therapy
dc.subjectArticle
dc.subjectArtificial ventilation
dc.subjectCase report
dc.subjectComputer assisted tomography
dc.subjectConsciousness
dc.subjectFever
dc.subjectGlasgow coma scale
dc.subjectHepatitis
dc.subjectHuman
dc.subjectIntensive care unit
dc.subjectJaundice
dc.subjectTonic clonic seizure
dc.subjectVomiting
dc.subjectAnalogs and derivatives
dc.subjectFatality
dc.titleChallenges in the treatment of acute fulminant hepatitis B: Case report and literature review
dc.typeArticle

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