Pediatric lipoblastomas: A case series

Abstract

Introduction: Lipoblastoma is a rare benign tumor originating from embryonic fat cells that occurs mostly within the first 3 years of life. It predominantly involves the subcutaneous tissue of the trunk and the extremities. However, in rare cases it can occur in other sites and the presentation can be the result of mass effect exerted on adjacent structures. Case presentation: We present 2 cases of lipoblastoma, both occurring in uncommon locations (retroperitoneum, neck) and exerting life-threatening mass effect. Both patients underwent complete surgical excision of the mass with preservation of vital structures and the final diagnosis was made by histopathology. The two patients were alive and doing well on follow up after surgery. Conclusion: Variability in presentation, anatomic locations, and patient characteristics necessitate a comprehensive understanding of lipoblastoma along with other entities that can mimic its presentation. The 2 cases of lipoblastoma presented in this case series, highlight the complexities related to diagnosing and managing lipoblastoma especially when occurring at unusual places and exerting a critical mass effect on vital structures. © 2023 The Authors