Comparison between nonmydriatic spectral domain optical coherence tomography and conventional ophthalmologic examination in detecting adult macular pathology

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dc.contributor.authorMehanna, Carl Joe
dc.contributor.authorAbdul Fattah, Maamoun
dc.contributor.authorGhazi, Nicola G.
dc.contributor.authorSheheitli, Huda A.
dc.contributor.authorHaddad, Sandra S.
dc.contributor.authorHaddad, Randa S.
dc.contributor.authorSalti, Haytham I.S.
dc.contributor.departmentOphthalmology
dc.contributor.facultyFaculty of Medicine (FM)
dc.contributor.institutionAmerican University of Beirut
dc.date.accessioned2025-01-24T12:08:37Z
dc.date.available2025-01-24T12:08:37Z
dc.date.issued2018
dc.description.abstractObjective: To compare nonmydriatic spectral domain optical coherence tomography (NMOCT) to comprehensive ophthalmologic evaluation (COE) in detecting adult macular abnormalities. Methods: This is a single-reader observational pilot study of adults older than 50 years with no known ophthalmologic problems to assess the correlation between NMOCT and COE in detecting macular abnormalities classified as epiretinal, intraretinal, subretinal, or a combination thereof. Subjects underwent NMOCT of the macula followed by COE which included a dilated fundus examination and ancillary tests as needed. Results: A total of 771 eyes of 406 patients were included. Cohen's kappa coefficient of agreement between NMOCT and COE for detecting any abnormality was high (0.90, p < 0.0001), with NMOCT having an overall sensitivity of 82.65% and specificity of 98.97%. Sensitivities and specificities of NMOCT in detecting each category of macular abnormalities were as follows: Epiretinal (86.36%, 99.73%), intraretinal (80.00%, 99.58%), and subretinal (88.89%, 99.73%), respectively. Conclusion: NMOCT is a promising tool for detecting adult macular abnormalities. © 2018 S. Karger AG, Basel. All rights reserved.
dc.identifier.doihttps://doi.org/10.1159/000484576
dc.identifier.eid2-s2.0-85047165279
dc.identifier.pmid29763887
dc.identifier.urihttp://hdl.handle.net/10938/31863
dc.language.isoen
dc.publisherS. Karger AG
dc.relation.ispartofOphthalmologica
dc.sourceScopus
dc.subjectAdult population
dc.subjectComprehensive ophthalmic evaluation
dc.subjectCorrelation
dc.subjectMacula
dc.subjectNonmydriatic optical coherence tomography
dc.subjectScreening
dc.subjectSensitivity
dc.subjectSpecificity
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectFemale
dc.subjectFollow-up studies
dc.subjectHumans
dc.subjectMacula lutea
dc.subjectMale
dc.subjectMiddle aged
dc.subjectMydriatics
dc.subjectOphthalmoscopy
dc.subjectPilot projects
dc.subjectProspective studies
dc.subjectReproducibility of results
dc.subjectRetinal diseases
dc.subjectTomography, optical coherence
dc.subjectMydriatic agent
dc.subjectAdult
dc.subjectArticle
dc.subjectControlled study
dc.subjectDiagnostic test accuracy study
dc.subjectEye examination
dc.subjectEye fundus
dc.subjectHuman
dc.subjectIntermethod comparison
dc.subjectMajor clinical study
dc.subjectNonmydriatic spectral domain optical coherence tomography
dc.subjectObservational study
dc.subjectOphthalmology
dc.subjectPilot study
dc.subjectRetina maculopathy
dc.subjectSensitivity and specificity
dc.subjectSpectral domain optical coherence tomography
dc.subjectComparative study
dc.subjectFollow up
dc.subjectOptical coherence tomography
dc.subjectPathology
dc.subjectProcedures
dc.subjectProspective study
dc.subjectReproducibility
dc.subjectRetina disease
dc.subjectRetina macula lutea
dc.subjectVery elderly
dc.titleComparison between nonmydriatic spectral domain optical coherence tomography and conventional ophthalmologic examination in detecting adult macular pathology
dc.typeArticle

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