High Intensity Focused Ultrasound (HIFU) is an ex-corporeal medical device that was first introduced in the 1940s for the treatment of neurological disorders and has been subjected to several improvements since then. It ...
Background: Sustained chronic liver injury originating from several factors including viral infection, alcohol consumption, and hepatitis may lead to hepatic fibrosis characterized by an imbalance between extracellular ...
E-3-(40-Hydroxy-30-adamantylbiphenyl-4-yl)acrylic acid (ST1926) is a novel orally available synthetic retinoid that is currently in phase I clinical trials. Synthetic retinoids are a group of compounds with Vitamin A ...
Adult T-cell leukemia (A TL) is an aggressive malignancy of activated T-cells caused by human T-cell lympbotrophic virus Type-I (I-ITLV-I) infections. Despite recent progress in A TL and HTLV-I negative peripheral T cell ...
DCQ (2-benzoyl-6,7-dichloro-3-phenylquinoxaline 1,4-dioxide) is a synthetic quin oxaline that enhances the sensitivity of cancerous cells to hypoxia. The aim of this study is to clarify the DNA damage potential and mechanism ...
Background and aims: Hypertension and obesity are key risk factors for cardiovascular disease. Obesity is associated with increased leptin production that may contribute to cardiovascular pathology through a multiplicity ...
347 million people worldwide suffer from Diabetes, and the prevalence of raised fasting blood glucose levels is increasing vastly by the year, and especially in the Middle East region. Worldwide, more than 3 million people ...
Background: Among the microvascular complications associated with diabetes, diabetic neuropathy (DN) is one of most commonly reported affecting 50percent - 70percent of diabetic subjects. Clinically, DN is characterized ...
In this thesis, we utilize DFT calculations to investigate the mechanism of
a fundamental chemical step that is widely implicated in homogenous catalysis,
namely insertion of unsaturated molecules into a metal-hydride bond ...
Knowledge of reaction mechanisms is of fundamental interest in chemistry. Understanding mechanisms can have immediate practical implications in the optimization of known reactions and the discovery of new ones. The advents ...