• Hepatitis C virus infection in the Middle East and North Africa mENA region: Injecting drug users (IDUs) is an under-investigated population 

  Ramia S.; Melhem N.M.; Kreidieh K. (HEIDELBERGTIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, 2012)

  Purpose: Investigation of the injecting drug users (IDUs) population is becoming extremely critical and timely in light of the recent evidence that IDUs now act as the core of hepatitis C virus (HCV) epidemics in developed ...
• Thymoquinone induces apoptosis in malignant T-cells via generation of ROS 

  Dergarabetian E.M.; Ghattass K.I.; El-Sitt S.B.; Al Mismar R.M.; El-Baba C.O.; Itani W.S.; Melhem N.M.; El-Hajj H.A.; Bazarbachi A.A.H.; Schneider-Stock R.; Gali-Muhtasib H.U. (, 2013)

  We show that HTLV-1 negative leukemia cells are more sensitive to TQ due to higher levels of drug-induced reactive oxygen species (ROS). PreG1 population in HTLV-1 negative Jurkat and CEM was higher than HTLV-1 transformed ...
• Reproductive tract infections (RTIs) among married non-pregnant women living in a low-income suburb of Beirut, Lebanon 

  Ramia S.; Kobeissi L.; el Kak F.; Shamra S.; Kreidieh K.; Zurayk H. (TRAMANIGLIOJIDC CENT OFF PORTO CONTE RICERCHE RES CTR, S P 55, PORTO CONTE CAPO CACCIA KM 8.400 LOC, TRAMANIGLIO, 07041, ITALY, 2012)

  Introduction: This study aimed to identify reproductive tract infections (RTIs) in married, non-pregnant women, aged 18 to 49 years, living in a low-income suburb of Beirut, and to investigate the relationship between ...
• Hepatitis D in the middle east and north africa (MENA): Update and challenges ahead 

  Melhem N.; Yazbek S.; Ramia S. (, 2012)

  Hepatitis D virus (HDV) is a defective RNA virus and its life cycle is dependent on hepatitis B virus (HBV). Worldwide, it is estimated that 15 to 20million individuals are HDV- infected representing approximately 5 percent ...
• The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8+ T cell responses 

  Melhem N.M.; Smith K.N.; Huang X.-L.; Colleton B.A.; Jiang W.; Mailliard R.B.; Mullins J.I.; Rinaldo C.R. (SAN DIEGO525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2014)

  It is unclear if HIV-1 variants lose the ability to prime naïve CD8+ cytotoxic T lymphocytes (CTL) during progressive, untreated infection. We conducted a comprehensive longitudinal analysis of viral evolution and its ...

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