Browsing by Author "Kobeissy, Firas"

Now showing items 1-16 of 16

ANTITUMOR EFFECT AND MECHANISM OF ACTION OF THE ATYPICAL SYNTHETIC RETINOID ST1926 ANALOGUE ON ADULT T-CELL LEUKEMIA/LYMPHOMA AND T LYMPHOMA

Nouaihed, Sahar Nazem (9/23/2020)

Adult T-cell leukemia/lymphoma (ATL) is a severe and rare T-cell malignancy caused by an aggressive human T-cell leukemia virus type-1 (HTLV-1) infection. ATL has a dismal prognosis and is highly resistant to chemotherapy, ...
Crosstalk between Bradykinin and Sphingosine-1-Phosphate Exacerbate Inflammation and Oxidative Stress in Microglia

Hassan, Nadine (9/6/2022)

Background: Neurodegenerative diseases (NDs) are a set of disorders that involve the death of neurons in the brain. These disorders are described as progressive and irreversible due to the brain’s limited regenerative ...
Dimorphism In The Association Between Diabetes And Depression: Unraveling Novel Biological Perspectives

Saad, Celine Georges (9/23/2020)

Background: Diabetes and depression are two disorders that are among the leading non-communicable diseases currently on the horizon worldwide. Recent epidemiological studies highlight the rising occurrence of depression ...
Effect of Succinate Dehydrogenase Inhibitors on Mouse Bone Marrow-Derived Macrophages Proliferation, Bioenergetics, and Immune Profile

Jelwan, Joseph (9/2/2022)

Background: Modern agriculture and food preservation standards require the use of fungicides to treat and prevent fungal contamination. Succinate dehydrogenase inhibitors (SDHIs) are one of the mostly used groups of ...
Impact of Succinate Dehydrogenase Inhibitors on THP-1 Derived Human Macrophages Viability, Mitochondrial Bioenergetics, and Immune Profile

Farhoud, Mohammad (12/20/2022)

Background: Succinate dehydrogenase inhibitors (SDHIs) are active compounds in a group of fungicides used extensively worldwide particularly to limit the proliferation of molds on plants and plants products. SDHIs mediate ...
Involvement Of The Kallikrein-Kinin System In Neuro-Inflammation

Hamati, Moussa (9/1/2022)

Introduction: Traumatic brain injury (TBI) is a major cause of disability and mortality worldwide. It can occur as a primary acute injury resulting from an exterior mechanical force or a secondary injury, which can become ...
MATHEMATICAL MODELING AND PARAMETER ESTIMATION OF BASAL-GANGLIA PROJECTING NEURONS IN THE ZEBRA FINCH

Sibahi, Ahmad (9/22/2020)

While the nonlinearity and complexity of biological phenomena keeps much of the intricate details of science mysterious, computational modeling can help unveil the dynamics and functionalities of such complex phenomena. ...
Neurodegeneration and Behavioral Changes Following Traumatic Brain Injury

EL Halabi, Doline Toufic (9/20/2021)

Traumatic Brain Injury (TBI) is one of the leading causes of disability and mortality in patients. Recent studies have shown a significant association between TBI and various neurological, cognitive, emotional, sensory, ...
Neurological, Cognitive, and Molecular Effects of Mitoquinone in Open Head Traumatic Brain Injury Mouse Model at Chronic Time-point

Haidar, Muhammad Ali Hussein (9/18/2021)

Traumatic brain injury (TBI) is a heterogeneous disease in terms of its origin, pathology, and prognosis. Globally, it is one of the leading causes of death and long-lasting disability. TBI is classified according to the ...
The Neuroprotective Effects of Edaravone in an Experimental Mouse Model of Traumatic Brain Injury

Mekhjian, Sarin (2/10/2023)

Traumatic brain injury (TBI) is a form of acquired brain injury that poses a significant threat to public health. Mild to severe TBI is rapidly being classified as a chronic disease, given that evidence indicates that ...
Non-Convulsive Status Epilepticus in a periadolescent rat model: evidence for alterations in hippocampal synaptic plasticity and later life disturbances in cognitive and emotional behaviors

Alturk, Sana (2/9/2021)

Background: Non-convulsive status epilepticus (NCSE) refer to prolonged seizures with minimal motor involvement. In clinical practice, these seizures are often underdiagnosed due to subtle manifestations such as transient ...
PANCREATIC AND KIDNEY PHANTOMS FOR THE EVALUATION OF ELECTROMAGNETIC SENSORS IN MONITORING THE COMPLICATIONS OF DIABETES AT 3.9 – 5.8 GHZ FREQUENCY RANGE

Jouni, Reem (2023-08-07)

Diabetes is a metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretions, action, or both. According to the International Diabetes Federation “IDF”, diabetes affects almost 537milion ...
Periprostatic Adipose Tissue Thromboinflammation Drives Early Neoplastic Alterations in a Rat Model of Mild Metabolic Dysfunction

AlZaim, Ibrahim (9/9/2022)

Emerging evidence links periprostatic adipose tissue (PPAT) inflammation, a consequence of metabolic impairment, to certain features of prostate cancer (PCa) aggressiveness. AT thromboinflammation, mediated by the proteolytic ...
ROLE OF NEWLY SYNTHESIZED CYCLOOXYGENASES IN ASPIRIN RESPONSIVENESS IN THE HUMAN MEGAKARYOBLASTIC CELL LINE MEG01

Fakih, Adham (2022-01-05)

Background: Aspirin is one of the most commonly used drugs in cardiovascular medicine. It interferes with platelet aggregation by inhibiting cyclooxygenases in blood platelets and megakaryocytes. Low-dose aspirin has at ...
Statins and Alzheimer's: The Controversy on its Protective Role

Al Moussawi, Nour (9/17/2021)

Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting millions of people worldwide. It is an irreversible, untreatable disease characterized by cognitive and behavioral dysfunctions such as memory, ...
Targets Identification of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomic Approach

Ayache, Zeinab (9/7/2022)

Abstract Background: Glioblastoma multiforme (GBM) is one of the most aggressive forms of malignant brain tumors. Despite the available therapies, the median survival rate of GBM patients does not exceed two years. Tumor ...

Now showing items 1-16 of 16

Search AUB ScholarWorks

Browse

All of AUB ScholarWorks

My Account

Copyright Statement

All materials included in the institutional repository are protected by copyright laws and are the property of their respective copyright holders. Materials may be used for non-commercial, educational, or research purposes only, and must be cited or attributed to the original source. Permission for any other use must be obtained from the copyright holder(s) directly. The American University of Beirut Libraries does not assume responsibility for any infringement of copyright laws that may occur as a result of the use of materials in the repository. If you believe that your copyright has been infringed upon in the repository, please contact the AUB Libraries immediately.

For further information, please contact us at scholarworks@aub.edu.lb

Browsing by Author "Kobeissy, Firas"

Browsing by Author "Kobeissy, Firas"

Search AUB ScholarWorks

Browse

All of AUB ScholarWorks

My Account

Copyright Statement