Adult T- cell leukemia (ATL) is a disease resistant to chemotherapy and has a ve ry poor prognosis where there remains no effective cure for it. It is caused by Human T-cell Lymphotropic Virus type 1 (HTLV-1). The aim of ...
Adult T-cell leukemia (ATL)-lymphoma is an aggressive neoplasm caused by human T -cell leukemia virus type -1 (HTLV-1). A regulatory oncogenic protein called Ta x plays an important role during ATL rendering the HTLV-1 ...
Adult T-cell leukemia-lymphoma (ATL) is an aggressive peripheral T-cell malignan cy caused by human T-cell lymphotropic virus type I (HTLV-I). ATL carries a poo r prognosis with a mean survival time of less than eight ...
HTLV-I associated adult T-cell leukemia-lymphoma (ATL) and HTLV-I-negative peripheral T-cell lymphomas carry poor prognosis mainly due to acquired resistance to chemotherapy. The mammalian Target of Rapamycin (mTOR) is a ...
Adult T-cell Leukemia (ATL) is one of the most common diseases associated with H uman T-cell Lymphotrophic Virus type I (HTLV-I) which was the first retrovirus t o be discovered in humans. ATL is a malignancy of activated ...
Human T-cell Lymphotropic Virus type 1 (HTLV-1) is the first retrovirus to be di scovered in humans. Among the diseases caused by HTLV-1 is Adult T-cell Leukemia (ATL), a malignancy of activated T lymphocytes. The survival ...
Retinoids play major roles in the regulation of cellular proliferation, differentiation, and apoptosis. Such functions have strongly supported the use of retinoids in cancer therapy, especially those of hematological ...
Adult T-cell leukemia (A TL) is an aggressive malignancy of activated T-cells caused by human T-cell lympbotrophic virus Type-I (I-ITLV-I) infections. Despite recent progress in A TL and HTLV-I negative peripheral T cell ...
N-(4-hydroxyphenyl)retinamide (HPR) is a synthetic retinoid that inhibits growth and induces apoptosis in many human cell lines including those that are resista nt to natural retinoids. Adult T-cell leukemia-lymphoma (ATL) ...