AUB ScholarWorks

Browsing by Subject "B Raf kinase"

Browsing by Subject "B Raf kinase"

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  • Saroufim M.; Habib R.; Karram S.; Youssef Massad C.; Taraif S.; Loya A.; Houreih M.A.; Sheikh S.S.; Amr S.S.; Satti M.; Oberkanins C.; Khalifeh I. (PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2014)
    BRAF mutation has been linked to the development of melanocytic tumors in homogeneous Caucasian cohorts. The role of solar UV radiation (UVR) in BRAF mutation status is poorly understood. We studied the epidemiology of ...
  • Saroufim M.; Novy M.; Taraif S.; Habib R.H.; Loya A.; Rauscher B.; Kriegshauser G.; Oberkanins C.; Khalifeh I. (Blackwell Publishing Ltd; HOBOKEN111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2014)
    Background Proto-oncogene B-Raf (BRAF) mutation rates have been reported in nevi and melanomas of homogeneous Caucasian cohorts. Objective To study the demographics of BRAF mutations in dysplastic nevi of populations with ...
  • Ahmadieh H.; Azar S.T. (, 2012)
    Thyroid cancer is among the most common endocrine malignancies. Genetic and environmental factors play an important role in the pathogenesis of differentiated thyroid cancer. Both have good prognosis but with frequent ...
  • Ahmadieh H.; Azar S.T. (, 2012)
    Thyroid cancer is among the most common endocrine malignancies. Genetic and environmental factors play an important role in the pathogenesis of differentiated thyroid cancer. Both have good prognosis but with frequent ...
  • Ahmadieh H.; Azar S.T. (, 2012)
    Thyroid cancer is among the most common endocrine malignancies. Genetic and environmental factors play an important role in the pathogenesis of differentiated thyroid cancer. Both have good prognosis but with frequent ...
  • Abbas O.; Miller D.D.; Bhawan J. (Lippincott Williams and Wilkins; PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2014)
    The incidence of cutaneous malignant melanoma has rapidly increased in recent years in all parts of the world, and melanoma is a leading cause of cancer death. As even relatively small melanomas may have metastatic potential, ...
  • Badr D.; Kurban M.; Abbas O. (HOBOKEN111 RIVER ST, HOBOKEN 07030-5774, NJ USA, 2013)
    For several decades, metformin has been used as an oral hypoglycaemic agent, where it is the first line of treatment in overweight and obese type 2 diabetic patients. This is because it decreases the hepatic glucose output ...
  • Temraz S.; Mukherji D.; Alameddine R.; Shamseddine A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2014)
    Metastatic colorectal cancer remains a lethal disease with a poor prognosis in the majority of patients. Multiple drug combinations have been developed in recent years that have significantly improved response rates and ...
  • Temraz S.; Mukherji D.; Alameddine R.; Shamseddine A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2014)
    Metastatic colorectal cancer remains a lethal disease with a poor prognosis in the majority of patients. Multiple drug combinations have been developed in recent years that have significantly improved response rates and ...
  • Temraz S.; Mukherji D.; Alameddine R.; Shamseddine A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2014)
    Metastatic colorectal cancer remains a lethal disease with a poor prognosis in the majority of patients. Multiple drug combinations have been developed in recent years that have significantly improved response rates and ...
  • Abu-Safieh L.; Abboud E.B.; Alkuraya H.; Shamseldin H.; Al-Enzi S.; Al-Abdi L.; Hashem M.; Colak D.; Jarallah A.; Ahmad H.; Bobis S.; Nemer G.; Bitar F.; Alkuraya F.S. (CAMBRIDGE600 TECHNOLOGY SQUARE, 5TH FLOOR, CAMBRIDGE, MA 02139 USA, 2011)
    Insulin-like growth factor binding proteins (IGFBPs) play important physiological functions through the modulation of IGF signaling as well as IGF-independent mechanisms. Despite the established role of IGFs in development, ...
  • Karram S.; Novy M.; Saroufim M.; Loya A.; Taraif S.; Houreih M.A.; Rauscher B.; Habib R.H.; Oberkanins C.; Khalifeh I. (PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2013)
    BACKGROUND:: BRAF mutations have been implicated in initiating promutagenic cellular melanocytic proliferation mostly based on homogeneous Western-based cohorts. Data addressing the possible interaction between exposure ...

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