Browsing Department of Chemistry by Title

Now showing items 1-20 of 357

2-Nucleobase-substituted 4,6-Diaminotriazine Analogs: Synthesis and Anti-cancer Activity in 5-Fluorouracil-sensitive and Resistant Colorectal Cancer Cells

Hamze, Khalil; Abdallah, Rola H.; Younis, Nour K.; Fardoun, Manal Muin; Darwiche, Nadine D.; Kobeissy, Firas H.; Iratni, Rabah; Bouhadir, Kamal Hani; Eid, Ali H. (Bentham Science Publishers, 2023)

Background: Cancer continues to be the second leading cause of death worldwide, with colorectal cancer (CRC) being the third most common type. Despite significant advances in cancer therapies, the current treatment of CRC ...
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells

Fardoun, Manal Muin; Iratni, Rabah; Dehaini, Hassan; Eid, Assaad A.; Ghaddar, Tarek H.; El-Elimat, Tamam M.; Alali, Feras Qasem; Badran, Adnan; Eid, Ali H.; Baydoun, Elias Abdel Hasan (MDPI AG, 2019)

Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ...
7-O-methylpunctatin, a novel homoisoflavonoid, inhibits phenotypic switch of human arteriolar smooth muscle cells

Fardoun, M.; Iratni, R.; Dehaini, H.; Eid, A.; Ghaddar, T.; El-Elimat, T.; Alali, F.; Badran, A.; Eid, A.H.; Baydoun, E. (MDPI AG, 2019)

Remodeling of arterioles is a pivotal event in the manifestation of many inflammation-based cardio-vasculopathologies, such as hypertension. During these remodeling events, vascular smooth muscle cells (VSMCs) switch from ...
A comparative study of the common persulfate activation techniques for the complete degradation of an NSAID: The case of ketoprofen

Amasha, Maya; Baalbaki, Abbas; Ghauch, Antoine (Elsevier B.V., 2018)

This work assessed the treatment of ketoprofen (KTP) using persulfate (PS) based Advanced Oxidation Process (AOP) activated thermally, chemically (Fe2+) or by UV. KTP degradation was optimized by manipulating several ...
A comparison of the electrical characteristics, liquid composition, and toxicant emissions of JUUL USA and JUUL UK e-cigarettes

Talih, Soha; Salman, Rola; El-Hage, Rachel; Karam, Ebrahim; Salam, Sally; Karaoghlanian, Nareg; El-Hellani, Ahmad; Saliba, Najat A.; Shihadeh, Alan Louis (Nature Research, 2020)

In 2018, JUUL entered the UK market, where EU regulations limit liquid nicotine concentration to 20 mg/mL, approximately one-third the level of JUUL products sold in the USA. We hypothesized that JUUL’s UK product was ...
A geostatistical approach for assessing population exposure to NO2 in a complex urban area (Beirut, Lebanon)

Badaro-Saliba, Nada; Adjizian-Gérard, Jocelyne; Zaarour, Rita; Abboud, Maher; Farah, W.; Saliba, Najat A.; Shihadeh, Alan Louis (Springer Science and Business Media, LLC, 2014)

Few studies in the Middle East region estimated the spatial distribution of air pollutants for exposure studies. This paper presents a geostatistical approach to assess background NO2 spatial distribution and the associated ...
A highly stable indium based metal organic framework for efficient arsenic removal from water

Atallah, Hala; Elcheikh Mahmoud, Mahmoud; Ali, Feysal M.; Lough, Alan John; Hmadeh, Mohamad (Royal Society of Chemistry, 2018)

A new porous indium metal organic framework namely (AUBM-1) was successfully synthesized via a solvothermal reaction of pyromellitic acid and indium chloride. Single crystal X-ray analysis revealed the formation of a 3D ...
A metathesis model for the dehydrogenative coupling of amines with alcohols and esters into carboxamides by milsteins [Ru(PNN)(CO)(H)] catalysts

Hasanayn, Faraj; Harb, Hassan (American Chemical Society, 2014)

Milsteins [Ru(PNN)(CO)(H)] catalyst (1-Ru) is known to mediate the dehydrogenative coupling of alcohols into esters. When it is used in alcohol-amine mixtures it catalyzes carboxamide formation selectively over esters and ...
A novel method to improve temperature forecast in data-scarce urban environments with application to the Urban Heat Island in Beirut

Ghadban, Mohamad; Baayoun, Abdelkader; Lakkis, Issam A.; Najem, Sara A.; Saliba, Najat A.; Shihadeh, Alan Louis (Elsevier B.V., 2020)

The urban heat island (UHI) effect has been the subject of much research due to its adverse effects on health, energy, and the environment. The objective of this work is to investigate the key parameters contributing to ...
A novel multi-functional fluorescent probe for Cu2+, Fe3+ and Ag+ based on a pyrimidine thiourea derivative

Hammud, Hassan Hasan; El-Dakdouki, Mohammad H.; Sonji, Nada M.; Sonji, Ghassan M.; Bouhadir, Kamal Hani (Bentham Science Publishers B.V., 2015)

A multi-functional “turn-off” fluorescent probe, N-[[(6-Amino-1,2,3,4-tetrahydro-1,3- dimethyl-2,4-dioxo-5-pyrimidinyl)amino]thioxomethyl]- benzamide, was synthesized and characterized. The probe showed high sensitivity ...
A Novel Study on the Self-Assembly Behavior of Poly(lactic- co-glycolic acid) Polymer Probed by Curcumin Fluorescence

Zakaria, Hanine; El-Kurdi, Riham; Patra, Digambara (American Chemical Society, 2022)

Understanding the self-assembly behavior of block copolymers is of great importance due to their usefulness in a wide range of applications. In this work, the physical properties of poly(lactic-co-glycolic acid) (PLGA ...
A Quick Method for the Determination of the Fraction of Freebase Nicotine in Electronic Cigarettes

Yassine, Amira; Antossian, Cynthia; El-Hage, Rachel; Saliba, Najat A. (American Chemical Society, 2023)

Recently, many electronic cigarettes (ECIGs) manufacturers have begun offering e-liquids, known as “nicotine salts”. These salts that have started gaining big popularity among users can be formed by adding weak acid to ...
A rapid and economical method for the quantification of hydrogen peroxide (H 2 O 2 ) using a modified HPLC apparatus

Tantawi, Omar N.; Baalbaki, Abbas; El Asmar, Rime; Ghauch, Antoine (Elsevier B.V., 2019)

H 2 O 2 is one of the most commonly used oxidants for the degradation of recalcitrant organic contaminants in advanced oxidation processes (AOPs). However, most research aiming to optimize AOPs is missing the monitoring ...
A Rational Design of Isoindigo-Based Conjugated Microporous n-Type Semiconductors for High Electron Mobility and Conductivity

Ranjeesh, Kayaramkodath Chandran; Rezk, Ayman; Martínez, José Ignacio; Gaber, Safa Ali; Merhi, Areej; Škorjanc, Tina; Finšgar, Matjaž; Luckachan, Gisha Elizabeth; Trabolsi, Ali; Kaafarani, Bilal R.; Nayfeh, Ammar M.; Shetty, Dinesh (John Wiley and Sons Inc, 2023)

The development of n-type organic semiconductors has evolved significantly slower in comparison to that of p-type organic semiconductors mainly due to the lack of electron-deficient building blocks with stability and ...
A Redox Isomerization Strategy for Accessing Modular Azobenzene Photoswitches with near Quantitative Bidirectional Photoconversion

Zhu, Jie S.; Larach, Julio M.; Tombari, Robert J.; Gingrich, Phillip W.; Bode, Stanley R.; Tuck, Jeremy R.; Warren, Hunter T.; Son, Jung-Ho; Duim, Whitney C.; Fettinger, James C.; Haddadin, Makhluf J.; Tantillo, Dean Joseph; Kurth, Mark J.; Olson, David E. (American Chemical Society, 2019)

Photoswitches capable of accessing two geometric states are highly desirable, especially if their design is modular and incorporates a pharmacophore tethering site. We describe a redox isomerization strategy for synthesizing ...
A short review on chemical properties, stability and nano-technological advances for curcumin delivery

Slika, Layal; Patra, Digambara (Taylor and Francis Ltd, 2020)

Introduction: Curcumin is a polyphenol found in turmeric that is derived from the rhizomes of Curcuma longa. Curcumin has received a worldwide attention due to being a major constituent of the traditional Chinese and Indian ...
A Survey on the Knowledge, Attitudes, and Practices of Lebanese Physicians Regarding Air Pollution

Assi, Hazem I.; Meouchy, Paul; El-Mahmoud, Ahmad; Massouh, Angela; Zerdan, Maroun Bou; Alameh, Ibrahim A.; Chamseddine, Nathalie; Kazarian, Houry; Zeineldine, Salah M.; Saliba, Najat A.; Noureddine, Samar Nayef (MDPI, 2022)

Introduction: Air pollution imposes a significant burden on public health. It is emerging as a modifiable risk factor for cancer, diabetes, and respiratory and cardiovascular diseases. This study aims to assess the knowledge, ...
A Systematic Review of Analytical Methods for the Separation of Nicotine Enantiomers and Evaluation of Nicotine Sources

Salam, Sally; El-Hajj Moussa, Fatima; El-Hage, Rachel; El-Hellani, Ahmad; Aoun Saliba, Najat (American Chemical Society, 2023)

The introduction of synthetic nicotine by the tobacco industry, also promoted as tobacco-free nicotine, presented new challenges for analytical chemists working in tobacco regulatory science to develop and optimize new ...
Accessing Multiple Classes of 2 H-Indazoles: Mechanistic Implications for the Cadogan and Davis-Beirut Reactions

Zhu, Jie S.; Li, Clarabella J.; Tsui, Kayi; Kraemer, Niklas; Son, Jung-Ho; Haddadin, Makhluf J.; Tantillo, Dean Joseph; Kurth, Mark J. (American Chemical Society, 2019)

The Cadogan cyclization is a robust but harsh method for the synthesis of 2H-indazoles, a valuable class of nitrogen heterocycles. Although nitrene generation by exhaustive deoxygenation is widely accepted as the operating ...
Acidity and complex formation studies of 3-(adenine-9-yl)-propionic and 3-(thymine-1-yl)-propionic acids in ethanol-water media

Hammud, Hassan Hasan; El-Shazly, Shawky; Sonji, Ghassan M.; Sonji, Nada M.; Bouhadir, Kamal Hani (Elsevier, 2015)

The ligands 3-(adenine-9-yl)propionic acid (AA) and 3-(thymine-1-yl)propionic acid (TA) were prepared by N9-alkylation of adenine and N1-alkylation of thymine with ethylacrylate in presence of a base catalyst, followed by ...

Now showing items 1-20 of 357

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Browsing Department of Chemistry by Title

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