• Hepatitis C virus infection in the Middle East and North Africa mENA region: Injecting drug users (IDUs) is an under-investigated population 

  Ramia S.; Melhem N.M.; Kreidieh K. (HEIDELBERGTIERGARTENSTRASSE 17, D-69121 HEIDELBERG, GERMANY, 2012)

  Purpose: Investigation of the injecting drug users (IDUs) population is becoming extremely critical and timely in light of the recent evidence that IDUs now act as the core of hepatitis C virus (HCV) epidemics in developed ...
• Thymoquinone induces apoptosis in malignant T-cells via generation of ROS 

  Dergarabetian E.M.; Ghattass K.I.; El-Sitt S.B.; Al Mismar R.M.; El-Baba C.O.; Itani W.S.; Melhem N.M.; El-Hajj H.A.; Bazarbachi A.A.H.; Schneider-Stock R.; Gali-Muhtasib H.U. (, 2013)

  We show that HTLV-1 negative leukemia cells are more sensitive to TQ due to higher levels of drug-induced reactive oxygen species (ROS). PreG1 population in HTLV-1 negative Jurkat and CEM was higher than HTLV-1 transformed ...
• The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8+ T cell responses 

  Melhem N.M.; Smith K.N.; Huang X.-L.; Colleton B.A.; Jiang W.; Mailliard R.B.; Mullins J.I.; Rinaldo C.R. (SAN DIEGO525 B ST, STE 1900, SAN DIEGO, CA 92101-4495 USA, 2014)

  It is unclear if HIV-1 variants lose the ability to prime naïve CD8+ cytotoxic T lymphocytes (CTL) during progressive, untreated infection. We conducted a comprehensive longitudinal analysis of viral evolution and its ...
• Reproductive tract infections (RTIs) among married non-pregnant women living in a low-income suburb of Beirut, Lebanon 

  Ramia S.; Kobeissi L.; el Kak F.; Shamra S.; Kreidieh K.; Zurayk H. (TRAMANIGLIOJIDC CENT OFF PORTO CONTE RICERCHE RES CTR, S P 55, PORTO CONTE CAPO CACCIA KM 8.400 LOC, TRAMANIGLIO, 07041, ITALY, 2012)

  Introduction: This study aimed to identify reproductive tract infections (RTIs) in married, non-pregnant women, aged 18 to 49 years, living in a low-income suburb of Beirut, and to investigate the relationship between ...
• Hepatitis D in the middle east and north africa (MENA): Update and challenges ahead 

  Melhem N.; Yazbek S.; Ramia S. (, 2012)

  Hepatitis D virus (HDV) is a defective RNA virus and its life cycle is dependent on hepatitis B virus (HBV). Worldwide, it is estimated that 15 to 20million individuals are HDV- infected representing approximately 5 percent ...
• Hepatitis B virus DNA in serum of 'anti-HBc only'-positive healthy Lebanese blood donors: significance and possible implications 

  El-Zaatari M.; Kazma H.; Naboulsi-Majzoub M.; Haidar M.; Ramlawi F.; Mahfoud Z.; Ramia S. (LONDON32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND, 2007)

  Transmission of HBV infection through transfusion of HBsAg-negative blood has been documented. It is evident that low levels of HBV-DNA remain detectable in serum and liver tissue of some patients who clear HbsAg, and that ...
• Genotypes of hepatitis C virus (HCV) among positive Lebanese patients: Comparison of data with that from other Middle Eastern countries 

  Sharara A.I.; Ramia S.; Ramlawi F.; Fares J.E.; Klayme S.; Naman R. (NEW YORK32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA, 2007)

  Recently we identified hepatitis C virus (HCV) genotype 4 as the principle genotype among Lebanese thalassaemics. In an attempt to confirm the predominance of genotype 4 in Lebanon and perhaps in the Middle East, genotyping ...
• Occult hepatitis B virus infection in HIV-infected Lebanese patients with isolated antibodies to hepatitis B core antigen 

  Ramia S.; Mokhbat J.; Ramlawi F.; El-Zaatari M. (LONDON1 WIMPOLE STREET, LONDON W1G 0AE, ENGLAND, 2008)

  The presence of hepatitis B virus (HBV) serological markers have been investigated in 101 Lebanese patients (69 men, 32 women; mean age 32.7 ± 1.7 years) infected with human immunodeficiency virus type 1 (HIV-1). Seven ...
• Distribution of hepatitis C virus genotypes among injecting drug users in Lebanon 

  Mahfoud Z.; Kassak K.; Kreidieh K.; Shamra S.; Ramia S. (LONDON236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND, 2010)

  Background: The aim of this study is to determine the prevalence of anti-HCV among injecting drug users (IDUs) in Lebanon, to establish the current prevalence of HCV genotypes in this population and to determine whether ...
• Hepatitis B virus and hepatitis C virus infections among female sex workers and men who have sex with men in Lebanon: Prevalence, risk behaviour and immune status 

  Kassak K.; Mahfoud Z.; Kreidieh K.; Shamra S.; Afifi R.; Ramia S. (COLLINGWOOD150 OXFORD ST, PO BOX 1139, COLLINGWOOD, VICTORIA 3066, AUSTRALIA, 2011)

  Background: The aim of our study was to study the prevalence of and the risk behaviours associated with the hepatitis B virus (HBV) and hepatitis C virus (HCV) infections among two high-risk groups: female sex workers (FSW) ...
• Current prevalence of hepatitis delta virus (HDV) infection and the range of HDV genotypes in Lebanon 

  Ramia S.; El-zaatari M.; Sharara A.I.; Ramlawi F.; Farhat B. (NEW YORK32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA, 2007)

  Recently the prevalence of hepatitis B virus (HBV) genotypes and the association between these genotypes and the clinical status of HBV-infected patients were recently investigated in the Lebanese population. The aim of ...
• Occult hepatitis B virus infection in Lebanese patients with chronic hepatitis C liver disease 

  Ramia S.; Sharara A.I.; El-Zaatari M.; Ramlawi F.; Mahfoud Z. (NEW YORK233 SPRING STREET, NEW YORK, NY 10013 USA, 2008)

  Occult hepatitis B virus (HBV) infection, characterised by the presence of HBV infection with undetectable hepatitis B surface antigen (HBsAg), was investigated in 98 Lebanese patients with chronic hepatitis C liver disease ...
• Occult hepatitis B virus infection in HIV-infected Lebanese patients with isolated antibodies to hepatitis B core antigen 

  Ramia S.; Mokhbat J.; Ramlawi F.; El-Zaatari M. (LONDON1 WIMPOLE STREET, LONDON W1G 0AE, ENGLAND, 2008)

  The presence of hepatitis B virus (HBV) serological markers have been investigated in 101 Lebanese patients (69 men, 32 women; mean age 32.7 ± 1.7 years) infected with human immunodeficiency virus type 1 (HIV-1). Seven ...
• Prevalence of antibodies to human immunodeficiency virus (HIV), hepatitis B and hepatitis C and risk factors in prisoners in Lebanon 

  Mahfoud Z.; Kassak K.; Kreidieh K.; Shamra S.; Ramia S. (TRAMANIGLIOJIDC CENT OFF PORTO CONTE RICERCHE RES CTR, S P 55, PORTO CONTE CAPO CACCIA KM 8.400 LOC, TRAMANIGLIO, 07041, ITALY, 2010)

  Background: People admitted to correctional facilities often have a history of risky behaviours which frequently lead to transmission of blood-borne viruses, such as human immunodeficiency virus (HIV), hepatitis B virus ...
• Occult hepatitis B virus infection in Lebanese patients with chronic hepatitis C liver disease 

  Ramia S.; Sharara A.I.; El-Zaatari M.; Ramlawi F.; Mahfoud Z. (NEW YORK233 SPRING STREET, NEW YORK, NY 10013 USA, 2008)

  Occult hepatitis B virus (HBV) infection, characterised by the presence of HBV infection with undetectable hepatitis B surface antigen (HBsAg), was investigated in 98 Lebanese patients with chronic hepatitis C liver disease ...
• Distribution of hepatitis C virus genotypes in the Middle East 

  Ramia S.; Eid-Fares J. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2006)

  It is well established that hepatitis C develops into cirrhosis of the liver and hepatocellular carcinoma (HCC) both of which are fatal diseases. The World Health Organization estimates that there are at least 21.3 million ...
• Frequency and significance of antibodies against hepatitis B core (anti-HBc) antigen as the only serological marker for hepatitis B infection in Lebanese blood donors 

  Ramia S.; Ramlawi F.; Kanaan M.; Klayme S.; Naman R. (NEW YORK40 WEST 20TH ST, NEW YORK, NY 10011-4211 USA, 2005)

  During a 2-year period, blood samples from 2505 Lebanese blood donors were chosen at random, at various periods of time at one blood donation centre (Hotel Dieu de France, Beirut, Lebanon) and were screened for markers of ...
• Distribution of hepatitis C virus genotypes in the Middle East 

  Ramia S.; Eid-Fares J. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2006)

  It is well established that hepatitis C develops into cirrhosis of the liver and hepatocellular carcinoma (HCC) both of which are fatal diseases. The World Health Organization estimates that there are at least 21.3 million ...
• Current prevalence of hepatitis delta virus (HDV) infection and the range of HDV genotypes in Lebanon 

  Ramia S.; El-zaatari M.; Sharara A.I.; Ramlawi F.; Farhat B. (NEW YORK32 AVENUE OF THE AMERICAS, NEW YORK, NY 10013-2473 USA, 2007)

  Recently the prevalence of hepatitis B virus (HBV) genotypes and the association between these genotypes and the clinical status of HBV-infected patients were recently investigated in the Lebanese population. The aim of ...
• Frequency and significance of antibodies against hepatitis B core (anti-HBc) antigen as the only serological marker for hepatitis B infection in Lebanese blood donors 

  Ramia S.; Ramlawi F.; Kanaan M.; Klayme S.; Naman R. (NEW YORK40 WEST 20TH ST, NEW YORK, NY 10011-4211 USA, 2005)

  During a 2-year period, blood samples from 2505 Lebanese blood donors were chosen at random, at various periods of time at one blood donation centre (Hotel Dieu de France, Beirut, Lebanon) and were screened for markers of ...

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