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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Now showing items 14-33 of 51

Frequency of the CCR5-delta 32 chemokine receptor gene mutation in the Lebanese population

Karam W.; Jurjus R.; Khoury N.; Khansa H.; Assad C.; Zalloua P.; Jurjus A. (, 2004)

A direct correlation between HIV infection and mutation in the chemokine receptor (CCR5) gene has been established. However, such correlation has never been investigated in Lebanon. We report the frequency of the CCR5-delta ...
Genes for diabetic nephropathy: Sweet prospects on the horizon

Karnib H.H.; Chua S.; Gharavi A.G. (NEW YORK75 VARICK STREET, 9TH FLOOR, NEW YORK, NY 10013-1917 USA, 2007)

Familial aggregation of diabetic nephropathy has suggested an important role for hereditary factors in the development of this trait. Österholm et al. provide further evidence that a gene on chromosome 3q confers susceptibility ...
Ginseng (Panax quinquefolius) attenuates leptin-induced cardiac hypertrophy through inhibition of p115Rho guanine nucleotide exchange factor-RhoA-Rho- associated, coiled-coil containing protein kinase-dependent mitogen-activated protein kinase pathway act

Moey M.; Rajapurohitam V.; Zeidan A.; Karmazyn M. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814-3995 USA, 2011)

Leptin is a 16-kDa peptide primarily derived from white adipocytes and is typically elevated in plasma of obese individuals. Although leptin plays a critical role in appetite regulation, leptin receptors have been identified ...
Human dental pulp cell apoptosis: Immunohistochemical study after applying orthodontic traction

Leone A.; Angelova Volponi A.; Campanella C.; Guarnotta C.; Abdallah Hajj Hussein I.; Cappello F.; Gerbino A.; Jurjus A. (SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2012)

The aim of this study was to compare human dental pulp stress and programmed cell death after 3 and 6 months of orthodontic treatments by assessing the degree of apoptosis and related proteins. Human dental pulps were ...
IFPA Meeting 2012 Workshop Report II: Epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta

Ahmed M.S.; Aleksunes L.M.; Boeuf P.; Chung M.K.; Daoud G.; Desoye G.; Diaz P.; Golos T.G.; Illsley N.P.; Kikuchi K.; Komatsu R.; Lao T.; Morales-Prieto D.M.; Nanovskaya T.; Nobuzane T.; Roberts C.T.; Saffery R.; Tamura I.; Tamura K.; Than N.G.; Tomi M.; (LONDON32 JAMESTOWN RD, LONDON NW1 7BY, ENGLAND, 2013)

Workshops are an important part of the IFPA annual meeting as they allow for discussion of specialized topics. At IFPA meeting 2012 there were twelve themed workshops, four of which are summarized in this report. These ...
Immunohistochemical expression of apoptotic factors, cytokeratins, and metalloproteinase-9 in periapical and epithelialized gingival lesions

Leone A.; Uzzo M.L.; Rappa F.; Hussein I.A.H.; Gerbino A.; Spatola G.F.; Jurjus A. (GDANSKUL SWIETOKRZYSKA 73, 80-180 GDANSK, POLAND, 2012)

The aim of the study was to assess the involvement of apoptotic factors, cytokeratins and metalloproteinase- 9 in the histogenesis of both Epithelialized Gingival Lesions (EGL) and Periapical Lesions (PAL). 55 consecutive ...
Inflammatory mediators released following application of irritants on the rat injured incisors. The effect of treatment with anti-inflammatory drugs

Chidiac J.J.; Al-Asmar B.; Rifai K.; Jabbur S.J.; Saade N.E. (LONDON24-28 OVAL RD, LONDON NW1 7DX, ENGLAND, 2009)

The exchange of fluids and chemicals between the tooth pulp and the periphery, through the dentinal tubules has been well documented. Application of irritants on the open tubules produces aversion in awake rats that can ...
Involvement of the α7-nicotinic acetylcholine receptors in the anti-inflammatory action of the thymulin-related peptide (PAT)

Safieh-Garabedian B.; Oz M.; Bey R.M.; Shamaa F.; Ashoor A.; El-Agnaf O.M.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2013)

Background and Purpose: Peptide analog of thymulin (PAT) has been shown to have anti-hyperalgesic and anti-inflammatory properties in animal models of inflammation. Recent reports suggest that the peripheral cholinergic ...
Kefir exhibits anti-proliferative and pro-apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion

Khoury N.; El-Hayek S.; Tarras O.; El-Sabban M.; El-Sibai M.; Rizk S. (Spandidos Publications; ATHENSPOB 18179, ATHENS, 116 10, GREECE, 2014)

Kefir, a fermented milk product, exhibits anti-tumoral activity in vivo; yet its mechanism of action remains elusive. Recent studies have focused on the mechanism of action of kefir on cancer cells in vitro. The current ...
Lactobacillus casei and Bifidobacterium lactis supplementation reduces tissue damage of intestinal mucosa and liver after 2,4,6-trinitrobenzenesulfonic acid treatment in mice

Bellavia M.; Rappa F.; Bello M.L.O.; Brecchia G.; Tomasello G.; Leone A.; Spatola G.; Uzzo M.L.; Bonaventura G.; David S.; Damiani P.; Hajj-Hussein I.; Zeenny M.N.; Jurjus A.; Schembri-Wismayer P.; Cocchi M.; Zummo G.; Farina F.; Gerbino A.; Cappello F.; (Biolife s.a.s.; SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2014)

Probiotics (PB) are living microorganisms that act as a commensal population in normal intestines and confer numerous beneficial effects on the host. The introduction of probiotics in the treatment of inflammatory bowel ...
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu M.K.; Abou-Kheir W.; Yin J.J.; Chang Y.-S.; Barrett B.; Suau F.; Casey O.; Chen W.-Y.; Fang L.; Hynes P.; Hsieh Y.-Y.; Liu Y.-N.; Huang J.; Kelly K. (Impact Journals LLC; ALBANY6211 TIPTON HOUSE, STE 6, ALBANY, NY 12203 USA, 2014)

Activation of EGFR signaling pathway leads to prostate cancer bone metastasis; however, therapies targeting EGFR have demonstrated limited effectiveness and led to drug resistance. miR-203 levels are down-regulated in ...
Mammalian target of rapamycin regulates nox4-Mediated podocyte depletion in diabetic renal injury

Eid A.A.; Ford B.M.; Bhandary B.; Cavaglieri R.D.C.; Block K.; Barnes J.L.; Gorin Y.; Choudhury G.G.; Abboud H.E. (ALEXANDRIA1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA, 2013)

Podocyte apoptosis is a critical mechanism for excessive loss of urinary albumin that eventuates in kidney fibrosis. Pharmacological doses of the mammalian target of rapamycin (mTOR) inhibitor rapamycin reduce albuminuria ...
Modified technique for the exposure of the inferior alveolar nerve in rats

Kassab A.; Hage M.; Jabbur S.J.; Chidiac J.J. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2013)

The inferior alveolar nerve (IAN), a branch of the mandibular division of the trigeminal nerve, is a major component of the neurovascular bundle along with the inferior alveolar artery and vein. In rats, when exposed using ...
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: Potential monitoring parameters

Leone A.; Uzzo M.L.; Gerbino A.; Tortorici S.; Tralongo P.; Cappello F.; Incandela S.; Spatola G.F.; Jurjus A.R. (Biolife s.a.s.; SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2014)

Churg-Strauss (CSS) syndrome is rare and of unknown etiology. It is associated with vasculitis, blood eosinophilia and granulomatosis, and affects multiple organs and systems at various stages of the disease. Specific ...
Modulation of β2 and β3 integrins in experimental colitis induced by iodoacetamide and enteropathogenic E. coli

Hajj-Hussein I.A.; Jurjus R.; Saliba J.; Ghanem S.; Diab R.; Bou Assi T.; Daouk H.; Leone A.; Jurjus A. (, 2013)

Integrins can modulate the infiltration of inflammatory cells and the secretion of various inflammatory mediators, essential players in the pathogenesis of colitis. This study explores the role of β2 and β3 integrin signaling ...
mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy

Zeidan A.; Hunter J.C.; Javadov S.; Karmazyn M. (, 2011)

Obesity is associated with increased leptin production which may contribute to cardiac hypertrophy. However, the mechanism of leptin-induced cardiac hypertrophy remains incompletely understood. The Rho family (RhoA, Rac1, ...
Mycobacterium tuberculosis spoligotypes circulating in the Lebanese population: A retrospective study [Spoligotypes de Mycobacterium tuberculosis circulant dans la population libanaise: Une étude rétrospective]

Bedrossian N.; Hamze M.; Rahmo A.K.; Jurjus A.; Saliba J.; Dabboussi F.; Karam W. (, 2013)

Genotyping Mycobacterium tuberculosis in Lebanon on the national level may be beneficial for assessing patients and monitoring the therapeutic response to DOTS. This study aimed to characterize the spoligotypes of clinical ...
Nociceptive behavior in animal models for peripheral neuropathy: Spinal and supraspinal mechanisms

Saade N.E.; Jabbur S.J. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2008)

Since the initial description by Wall [Wall, P.D., 1967. The laminar organization of dorsal horn and effects of descending impulses. J. Neurophysiol. 188, 403-423] of tonic descending inhibitory control of dorsal horn ...
Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes

Maalouf R.M.; Eid A.A.; Gorin Y.C.; Block K.; Escobar G.P.; Bailey S.; Abboud H.E. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA, 2012)

Oxidative stress contributes to diabetic cardiomyopathy. This study explored the role of the NADPH oxidase Nox4 as a source of reactive oxygen species (ROS) involved in the development of diabetic cardiomyopathy. ...
Occlusion of dentinal tubules and selective block of pulp innervation prevent the nociceptive behaviour induced in rats by intradental application of irritants

Rifai K.; Chidiac J.J.; Hawwa N.; Baliki M.; Jabbur S.J.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2004)

Objectives: Application of irritants on the exposed dentine of the incisors has been shown to produce aversive behaviour in awake rats. This study aims to demonstrate that the observed aversion is due to the infiltration ...

Now showing items 14-33 of 51

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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

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