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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Now showing items 21-40 of 51

Involvement of the α7-nicotinic acetylcholine receptors in the anti-inflammatory action of the thymulin-related peptide (PAT)

Safieh-Garabedian B.; Oz M.; Bey R.M.; Shamaa F.; Ashoor A.; El-Agnaf O.M.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2013)

Background and Purpose: Peptide analog of thymulin (PAT) has been shown to have anti-hyperalgesic and anti-inflammatory properties in animal models of inflammation. Recent reports suggest that the peripheral cholinergic ...
Kefir exhibits anti-proliferative and pro-apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion

Khoury N.; El-Hayek S.; Tarras O.; El-Sabban M.; El-Sibai M.; Rizk S. (Spandidos Publications; ATHENSPOB 18179, ATHENS, 116 10, GREECE, 2014)

Kefir, a fermented milk product, exhibits anti-tumoral activity in vivo; yet its mechanism of action remains elusive. Recent studies have focused on the mechanism of action of kefir on cancer cells in vitro. The current ...
Lactobacillus casei and Bifidobacterium lactis supplementation reduces tissue damage of intestinal mucosa and liver after 2,4,6-trinitrobenzenesulfonic acid treatment in mice

Bellavia M.; Rappa F.; Bello M.L.O.; Brecchia G.; Tomasello G.; Leone A.; Spatola G.; Uzzo M.L.; Bonaventura G.; David S.; Damiani P.; Hajj-Hussein I.; Zeenny M.N.; Jurjus A.; Schembri-Wismayer P.; Cocchi M.; Zummo G.; Farina F.; Gerbino A.; Cappello F.; (Biolife s.a.s.; SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2014)

Probiotics (PB) are living microorganisms that act as a commensal population in normal intestines and confer numerous beneficial effects on the host. The introduction of probiotics in the treatment of inflammatory bowel ...
Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu M.K.; Abou-Kheir W.; Yin J.J.; Chang Y.-S.; Barrett B.; Suau F.; Casey O.; Chen W.-Y.; Fang L.; Hynes P.; Hsieh Y.-Y.; Liu Y.-N.; Huang J.; Kelly K. (Impact Journals LLC; ALBANY6211 TIPTON HOUSE, STE 6, ALBANY, NY 12203 USA, 2014)

Activation of EGFR signaling pathway leads to prostate cancer bone metastasis; however, therapies targeting EGFR have demonstrated limited effectiveness and led to drug resistance. miR-203 levels are down-regulated in ...
Mammalian target of rapamycin regulates nox4-Mediated podocyte depletion in diabetic renal injury

Eid A.A.; Ford B.M.; Bhandary B.; Cavaglieri R.D.C.; Block K.; Barnes J.L.; Gorin Y.; Choudhury G.G.; Abboud H.E. (ALEXANDRIA1701 N BEAUREGARD ST, ALEXANDRIA, VA 22311-1717 USA, 2013)

Podocyte apoptosis is a critical mechanism for excessive loss of urinary albumin that eventuates in kidney fibrosis. Pharmacological doses of the mammalian target of rapamycin (mTOR) inhibitor rapamycin reduce albuminuria ...
Modified technique for the exposure of the inferior alveolar nerve in rats

Kassab A.; Hage M.; Jabbur S.J.; Chidiac J.J. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2013)

The inferior alveolar nerve (IAN), a branch of the mandibular division of the trigeminal nerve, is a major component of the neurovascular bundle along with the inferior alveolar artery and vein. In rats, when exposed using ...
Modulation of MMP-2 and MMP-9 in Churg-Strauss syndrome respiratory mucosa: Potential monitoring parameters

Leone A.; Uzzo M.L.; Gerbino A.; Tortorici S.; Tralongo P.; Cappello F.; Incandela S.; Spatola G.F.; Jurjus A.R. (Biolife s.a.s.; SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2014)

Churg-Strauss (CSS) syndrome is rare and of unknown etiology. It is associated with vasculitis, blood eosinophilia and granulomatosis, and affects multiple organs and systems at various stages of the disease. Specific ...
Modulation of β2 and β3 integrins in experimental colitis induced by iodoacetamide and enteropathogenic E. coli

Hajj-Hussein I.A.; Jurjus R.; Saliba J.; Ghanem S.; Diab R.; Bou Assi T.; Daouk H.; Leone A.; Jurjus A. (, 2013)

Integrins can modulate the infiltration of inflammatory cells and the secretion of various inflammatory mediators, essential players in the pathogenesis of colitis. This study explores the role of β2 and β3 integrin signaling ...
mTOR mediates RhoA-dependent leptin-induced cardiomyocyte hypertrophy

Zeidan A.; Hunter J.C.; Javadov S.; Karmazyn M. (, 2011)

Obesity is associated with increased leptin production which may contribute to cardiac hypertrophy. However, the mechanism of leptin-induced cardiac hypertrophy remains incompletely understood. The Rho family (RhoA, Rac1, ...
Mycobacterium tuberculosis spoligotypes circulating in the Lebanese population: A retrospective study [Spoligotypes de Mycobacterium tuberculosis circulant dans la population libanaise: Une étude rétrospective]

Bedrossian N.; Hamze M.; Rahmo A.K.; Jurjus A.; Saliba J.; Dabboussi F.; Karam W. (, 2013)

Genotyping Mycobacterium tuberculosis in Lebanon on the national level may be beneficial for assessing patients and monitoring the therapeutic response to DOTS. This study aimed to characterize the spoligotypes of clinical ...
Nociceptive behavior in animal models for peripheral neuropathy: Spinal and supraspinal mechanisms

Saade N.E.; Jabbur S.J. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2008)

Since the initial description by Wall [Wall, P.D., 1967. The laminar organization of dorsal horn and effects of descending impulses. J. Neurophysiol. 188, 403-423] of tonic descending inhibitory control of dorsal horn ...
Nox4-derived reactive oxygen species mediate cardiomyocyte injury in early type 1 diabetes

Maalouf R.M.; Eid A.A.; Gorin Y.C.; Block K.; Escobar G.P.; Bailey S.; Abboud H.E. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA, 2012)

Oxidative stress contributes to diabetic cardiomyopathy. This study explored the role of the NADPH oxidase Nox4 as a source of reactive oxygen species (ROS) involved in the development of diabetic cardiomyopathy. ...
Occlusion of dentinal tubules and selective block of pulp innervation prevent the nociceptive behaviour induced in rats by intradental application of irritants

Rifai K.; Chidiac J.J.; Hawwa N.; Baliki M.; Jabbur S.J.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2004)

Objectives: Application of irritants on the exposed dentine of the incisors has been shown to produce aversive behaviour in awake rats. This study aims to demonstrate that the observed aversion is due to the infiltration ...
Orthodontic stress Bcl-2 modulation and human odontoblast survival

Leone A.; Lipari L.; Uzzo M.L.; Spatola G.F.; Provenzano S.; Gerbino A.; Jurjus A.R. (SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2013)

This study assessed the effect of orthodontic traction on Bcl-2 expression and apoptosis in human dental pulp. It also explored, in absence of noxious stimuli the regeneration of odontoblasts during the entire life of the ...
Prevalence of IL-1β+3954 and IL-1α-889 polymorphisms in the Lebanese population and its association with the severity of adult chronic periodontitis

Tawil G.; Akl F.A.; Dagher M.F.; Karam W.; Abdallah Hajj Hussein I.; Leone A.; Jurjus A.R. (, 2012)

Pro-inflammatory cytokines, i.e., IL-1 mediate the inflammatory response and are genetically regulated in periodontal diseases. Strong association was found between the composite genotype allele 2 of IL-1β+3954 and IL-1α-889 ...
Prevention of RhoA activation and cofilin-mediated actin polymerization mediates the antihypertrophic effect of adenosine receptor agonists in angiotensin II- and endothelin-1-treated cardiomyocytes

Zeidan A.; Gan X.T.; Thomas A.; Karmazyn M. (DORDRECHTVAN GODEWIJCKSTRAAT 30, 3311 GZ DORDRECHT, NETHERLANDS, 2014)

Adenosine receptor activation has been shown to be associated with diminution of cardiac hypertrophy and it has been suggested that endogenously produced adenosine may serve to blunt pro-hypertrophic processes. In the ...
Probiotics, prebiotics and symbiotics in inflammatory bowel diseases: State-of-the-art and new insights

Sinagra E.; Tomasello G.; Cappello F.; Leone A.; Cottone M.; Bellavia M.; Rossi F.; Facella T.; Damiani P.; Zeenny M.N.; Damiani F.; Abruzzo A.; Damiano G.; Palumbo V.D.; Cocchi M.; Jurjus A.; Spinelli G.; Lo Monte A.I.; Raimondo D. (SILVA MARINA (TE)VIA S STEFANO 39 BIS, 64029 SILVA MARINA (TE), ITALY, 2013)

Inflammatory bowel disease (IBD) consists of two distinct clinical forms, ulcerative colitis (UC) and Crohn's disease (CD), with unknown aetiology, which nevertheless are considered to share almost identical pathophysiological ...
Rare variations of the left subclavian artery

Saadeh F.A.; El-Sabban M. (HOBOKENDIV JOHN WILEY and SONS INC, 111 RIVER ST, HOBOKEN, NJ 07030 USA, 2005)

The subclavian artery is a major constituent of the blood circulatory system. Its position in the root of the neck and its course through the interscalene triangle are significant. Its branches supply divers areas in the ...
Self-renewing Pten ---TP53 --- protospheres produce metastatic adenocarcinoma cell lines with multipotent progenitor activity

Abou-Kheir W.; Hynes P.G.; Martin P.; Yin J.J.; Liu Y.-N.; Seng V.; Lake R.; Spurrier J.; Kelly K. (SAN FRANCISCO185 BERRY ST, STE 1300, SAN FRANCISCO, CA 94107 USA, 2011)

Prostate cancers of luminal adenocarcinoma histology display a range of clinical behaviors. Although most prostate cancers are slow-growing and indolent, a proportion is aggressive, developing metastasis and resistance to ...
Spinal segmental and supraspinal mechanisms underlying the pain-relieving effects of spinal cord stimulation: An experimental study in a rat model of neuropathy

Barchini J.; Tchachaghian S.; Shamaa F.; Jabbur S.J.; Meyerson B.A.; Song Z.; Linderoth B.; Saade N.E. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2012)

Spinal cord stimulation (SCS) may alleviate certain forms of neuropathic pain; its mechanisms of action are, however, not fully understood. Previous studies have mainly been focused onto segmental spinal mechanisms, though ...

Now showing items 21-40 of 51

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Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

Browsing Anatomy, Cell Biology, and Physiology - Faculty Publications by Title

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