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Browsing Pathology and Laboratory Medicine by Title

Now showing items 2-21 of 389

A comparative study of systemic carcinogen exposure in waterpipe smokers, cigarette smokers and Non-Smokers

Al-Ali, Radwan; Rastam, Samer; Ibrahim, Iman; Bazzi, Asma; Fayad, Sanaa; Shihadeh, Alan Louis; Zaatari, Ghazi S.; Maziak, Wasim (BMJ Publishing Group, 2015)

Background In the past decade, waterpipe smoking— also known as hookah, shisha, narghileh—has increased among youth. The scarcity of rigorous studies linking waterpipe smoking to smoking-related diseases has hindered policy ...
A compilation of antimicrobial susceptibility data from a network of 13 Lebanese hospitals reflecting the national situation during 2015-2016

Moghnieh, Rima A.; Araj, George F.; Awad, Lyn S.; Daoud, Ziad D.; Mokhbat, Jacques Emile; Jisr, Tamima El; Abdallah, Dania Issam; Azar, Nadim; Irani-Hakimeh, Noha; Balkis, Maher M.; Youssef, Mona M.; Karayakoupoglou, Gilbert; Hamzé, Monzer M.; Matar, Madonna J.; Atoui, Rola; Abboud, Edmond; Feghali, Rita; Yared, Nadine A.; Husni, Rola N. (BioMed Central Ltd., 2019)

Background: There is a lack of official national antimicrobial resistance (AMR) data in Lebanon. Individual hospitals generate their own antibiotic susceptibility data in the form of yearly pamphlets. Methods: In this ...
A novel cystic fibrosis gene mutation c.2490insT in a Palestinian patient: A case report and review of the literature

Chami, Hassan A.; Abou Arbid, Samer A.; Badra, Rebecca; Farra, Chantal G. (Medknow Publications, 2017)

We report the case of a 19-year-old male patient of Palestinian descent, who presented with a 1-year history of recurrent Pseudomonas aeruginosa respiratory infections, weight loss, chronic diarrhea, and a normal chloride ...
A novel mutation in the RSPO4 gene in a patient with autosomal recessive anonychia

Khalil, Samar; Hayashi, Ryota; Daou, Laetitia; Staiteieh, Soumaiah Abou; Abbas, Ossama M.; Bergqvist, Christina; Nemer, Georges M.; Shimomura, Yutaka; Kurban, Mazen S. (Blackwell Publishing Ltd, 2017)

The Wnt signalling pathway is a major pathway involved in the embryogenic development of the various organs of the body. Appropriate signalling in this pathway relies on the proper functioning of several proteins including ...
A patient with a protuberant fibro-osseous lesion of the temporal bone

Maroun, Christopher A.; Khalifeh, Ibrahim M.; Faddoul, Daniel S.; Zaytoun, George M.; Moukarbel, Roger V. (Lippincott Williams and Wilkins, 2019)

Protuberant fibro-osseous lesion of the temporal bone, otherwise known as Bullough's lesion, is a rare, benign exophytic fibro-osseous tumor. In this brief report, we present a case of a 61-year-old woman with a history ...
A Pin1/PML/P53 axis activated by retinoic acid in NPM-1c acute myeloid leukemia

Hleihel, Rita S.; El-Hajj, Hiba Ahmad; Wu, Hsinchieh; Berthier, Caroline P.; Zhu, Honghu; Massoud, Radwan; Chakhachiro, Zaher I.; El-Sabban, Marwan E.; de Thȩ, Hugues B.; Bazarbachi, Ali Abdul Hamid (Ferrata Storti Foundation, 2021)

Retinoic acid (RA) was proposed to increase survival of chemotherapy-treated patients with nucleophosmin-1 (NPM-1c)-mutated acute myeloid leukemia. We reported that, ex vivo, RA triggers NPM-1c degradation, P53 activation ...
A synonymous variant in MYO15A enriched in the Ashkenazi Jewish population causes autosomal recessive hearing loss due to abnormal splicing

Hirsch, Yoel; Tangshewinsirikul, Chayada; Booth, Kevin T.A.; Azaiez, Hela; Yefet, Devorah; Quint, Adina; Weiden, Tzvi; Brownstein, Zippora N.; Macarov, Michal; Davidov, Bella; Pappas, John Georgios; Rabin, Rachel Allison; Kenna, Margaret A.; Oza, Andrea M.; Lafferty, Katherine A.; Amr, Sami S.; Rehm, Heidi L.; Kolbe, Diana L.; Frees, Kathy L.; Nishimura, Carla J.; Luo, Minjie; Farra, Chantal G.; Morton, Cynthia Casson; Scher, Sholem Y.; Ekstein, Josef; Avraham, Karen B.; Smith, Richard J.H.; Shen, Jun (Springer Nature, 2021)

Nonsyndromic hearing loss is genetically heterogeneous. Despite comprehensive genetic testing, many cases remain unsolved because the clinical significance of identified variants is uncertain or because biallelic pathogenic ...
A woman with metastatic pancreatic neuroendocrine tumor

Shoushtari, Alexander N.; Covey, Anne M.; Zaatari, Ghazi S.; Shamseddine, Ali I.; Epstein, Andrew S.; Haydar, Ali A.; Naghy, Mohamed; Mukherji, Deborah M.; Kelsen, David P.; Abou-Alfa, Ghassan Khaled; O'Reilly, Eileen Mary (International Society of Gastrointestinal Oncology, 2014)
Acquired centromeric heteromorphism of chromosome 7 yields discordant results between fluorescent in situ hybridization and karyotype analysis in a child with severe congenital neutropenia

Farra, Chantal G.; Raimondi, Susana Catalina; Abboud, Miguel Raul (Taylor and Francis Ltd, 2019)

Monosomy 7 is an indicator of malignant transformation in patients with different subtypes of severe congenital neutropenias (SCNs). We present the case of a 5-year-old male diagnosed with SCN. Standard karyotype and ...
Activating BRAF Mutations Detected in Mixed Hurthle Cell Carcinoma and Multifocal Papillary Carcinoma of the Thyroid Gland: Report of an Unusual Case and Review of the Literature

Sinno, Sara A.J.; Choucair, Mahmoud K.; Nasrallah, Mona P.; Wadi, Lara Carine; Jabbour, Mark N.; Nassif, Samer R. (SAGE Publications Inc., 2016)

Despite the increase in the incidence of thyroid carcinomas, the occurrence of collision tumors in the thyroid remains a rare event. We present the case of a 69-year-old female who presented to the emergency department ...
Activity of ceftolozane/tazobactam against commonly encountered antimicrobial resistant Gram-negative bacteria in Lebanon

Araj, George F.; Berjawi, Dana M.; Musharrafieh, Umayya; Beayni, Nancy K.El (Journal of Infection in Developing Countries, 2020)

Introduction: In view of the continuous rise in Gram-negative bacterial resistance and limited treatment options, Ceftolozane/tazobactam (C/T) is a newly introduced antimicrobial agent in Lebanon for its demonstrated ...
Acute disseminated encephalomyelitis and reactivation of cerebral toxoplasmosis in a child: Case report

Bannoura, Sami; El Hajj, Rana H.; Khalifeh, Ibrahim M.; El-Hajj, Hiba Ahmad (Elsevier Ltd, 2018)

Toxoplasma gondii is an opportunistic parasite that infects a broad range of hosts including humans. The chronic latent phase of the disease manifests as intra-neuronal cerebral cysts tightly controlled by the host immune ...
Acute Exposure to Electronic and Combustible Cigarette Aerosols: Effects in an Animal Model and in Human Alveolar Cells

Husari, Ahmad W.; Shihadeh, Alan Louis; Talih, Soha; Hashem, Yasmine; El-Sabban, Marwan E.; Zaatari, Ghazi S. (Oxford University Press, 2016)

Background: Smoking electronic cigarettes (ECIG) is promoted as a safer alternative to smoking combustible cigarettes. This study investigates the effects of ECIG aerosol and cigarette smoke (CS) in an animal model and in ...
Acute kidney injury secondary to obstructive bladder malakoplakia: a case report

Jdiaa, Sara S.; Degheili, Jad A.; Matar, Charbel F.; Mocadie, Michele F.; Khaled, Chirine S.; El Zakhem, Aline M. (Springer Science and Business Media Deutschland GmbH, 2023)

Background: Malakoplakia is a rare granulomatous inflammatory condition that can affect immunosuppressed patients. The genitourinary system is the most involved organ. We present a case of kidney failure caused by obstructing ...
Acute promyelocytic leukemia with increased bone marrow reticulin fibrosis: Description of three cases and review of the literature

Abou Dalle, Iman; Nassif, Samer R.; Bazarbachi, Ali Abdul Hamid (King Faisal Specialist Hospital and Research Centre, 2018)

Pathologic increase in bone marrow reticulin fibrosis can be present in many malignant hematopoietic diseases. In acute leukemia, one-third of patients have some degree of marrow reticulin fibrosis at presentation, which ...
ADAM3A copy number gains occur in a subset of conjunctival squamous cell carcinoma and its high grade precursors

Vizcaíno, Maria Adelita; Tabbarah, Abeer Z.; Asnaghi, Laura; Maktabi, Azza M.Y.; Eghrari, Allen Omid; Srikumaran, Divya; Eberhart, Charles G.; Rodríguez, Fausto J. (W.B. Saunders, 2019)

Conjunctival squamous cell carcinoma (cSCC) and its precursors are among the most frequent ocular surface neoplasms worldwide. Copy gain of 8p11.22 and ADAM3A overexpression have been recently identified in invasive cSCC. ...
Adult ocular toxocariasis mimicking ciliary body malignancy

Mansour, Ahmad Mohammed Farid Mahmoud; Abiad, Bachir H.; Boulos, Fouad I.; Alameddine, Ramzi M.; Maalouf, Fadi C.; Bou Ghannam, Alaa S.; Hamam, Rola N. (Hindawi Limited, 2014)

Purpose. To discuss an unusual presentation of ocular toxocariasis.; Methods. Case report.; Results. A 40-year-old woman presented with decreased vision in the left eye with a long history of recurrent red eye from uveitis. ...
Alpha thalassemia allelic frequency in Lebanon

Farra, Chantal G.; Badra, Rebecca; Fares, Farah; Muwakkit, Samar A.; Dbaibo, Ghassan S.; Al-Dabbous, Ibrahim A.; Ashkar, Hanine; Mounsef, Carla; Abboud, Miguel Raul (John Wiley and Sons Inc., 2015)

Background: Hemoglobinopathies are the most common reported monogenic disorders worldwide. It is well established that Mediterranean and Arab countries are high risk areas for thalassemia in general, and for alpha thalassemia ...
Alternative lengthening of telomeres, ATRX loss and H3-K27M mutations in histologically defined pilocytic astrocytoma with anaplasia

Rodríguez, Fausto J.; Brosnan-Cashman, Jacqueline A.; Allen, Sariah J.; Vizcaíno, Maria Adelita; Giannini, Caterina; Camelo-Piragua, Sandra Ines; Webb, Milad; Matsushita, Marcus De Medeiros; Wadhwani, Nitin R.; Tabbarah, Abeer Z.; Hamideh, Dima; Jiang, Liqun; Chen, Liam L.; Arvanitis, Leonidas D.; Alnajar, Hussein H.; Barber, John R.; Rodríguez-Velasco, Alicia; Orr, Brent A.; Heaphy, Christopher M. (Blackwell Publishing Ltd, 2019)

Anaplasia may be identified in a subset of tumors with a presumed pilocytic astrocytoma (PA) component or piloid features, which may be associated with aggressive behavior, but the biologic basis of this change remains ...
Ambient air concentrations and risk assessment of selected organochlorine pesticides (OCPs) across five Middle Eastern countries

Gevao, Bondi; Kurt-Karakus, Perihan Binnur; Birgul, Askin; Martínez-Guijarro, Karell; Sukhn, Carol M.S.; Krishnan, Divya; Rajagopalan, Smitha; Hajeyah, Mariam; Bahloul, Majed; Alshemmari, Hassan; Orif, Mohammed Ibrahim (OAE Publishing Inc., 2022)

This paper presents data obtained from concurrently deployed polyurethane foam disk passive samplers in Kuwait, Turkey, Lebanon, Saudi Arabia, and Oman between January and October 2018. The study’s main goal was to initiate ...

Now showing items 2-21 of 389

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Browsing Pathology and Laboratory Medicine by Title

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