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Now showing items 197-216 of 389

Ki-67 expression predicts biochemical recurrence after radical prostatectomy in the setting of positive surgical margins

Shahait, Mohammed; Nassif, Samer R.; Tamim, Hani Mohammed; Mukherji, Deborah M.; Hijazi, Maya M.; El-Sabban, Marwan E.; Khauli, Raja Bahjat; Bulbul, Muhammad Ahmad; Abou-Kheir, Wassim G.; El Hajj, Albert Elias (BioMed Central Ltd., 2018)

Background: Positive surgical margin (PSM) is a predictor of biochemical recurrence (BCR) following radical prostatectomy (RP). Attempts to stratify PSM based on linear length, Gleason score, location and number have failed ...
Ki67 and P53 in Relation to Disease Progression in Metastatic Pancreatic Cancer: a Single Institution Analysis

Temraz, Sally N.; Shamseddine, Ali I.; Mukherji, Deborah M.; Charafeddine, Maya A.; Tfayli, Arafat Hussein; Assi, Hazem I.; Hammoud, Miza Salim; Makki, Iman S.; Nassif, Samer R. (Springer Netherlands, 2019)

We investigated the expression patterns of Ki67 and p53 in metastatic pancreatic adenocarcinomas and analyzed their relationship with disease progression-free survival (PFS) and overall survival (OS) in the overall study ...
Killer cell Immunoglobulin-like Receptors (KIRs) and hematopoietic stem cell transplantation outcomes. A review of the literature

Rammal, Rayan; Haddad, Joseph; Mahfouz, Rami A.R. (Elsevier B.V., 2017)

Natural killer (NK) cells are a type of cytotoxic lymphocytes that have an important role in innate immunity. These cells are equipped with a number of surface receptors, inhibitory, activating, or both, that control their ...
KIR genotype distribution among Lebanese patients with Hodgkin's lymphoma

Hoteit, Rouba M.; Abboud, Miguel Raul; Bazarbachi, Ali Abdul Hamid; Salem, Ziad M.; Shammaa, Dina M.R.; Zaatari, Ghazi S.; Mahfouz, Rami A.R. (Elsevier, 2015)

Introduction: In addition to their important role in fighting infection, natural killer cells are cytotoxic to cancer cells. Studies demonstrated that some KIR genes were responsible for the reduction of the risk of Hodgkin's ...
KIR genotype distribution among patients with chronic lymphocytic leukemia: Is there a role for KIR 2DS4 and KIR 2DS5 genes?

Hoteit, Rouba M.; Bazarbachi, Ali Abdul Hamid; Antar, Ahmad I.; Salem, Ziad M.; Shammaa, Dina M.R.; Mahfouz, Rami A.R. (Elsevier Inc, 2016)

Introduction The function of natural killer (NK) cells is regulated by different antigen receptors including killer immunoglobulin-like receptors (KIR). In addition to their important role in fighting infection, natural ...
KIR genotype distribution among patients with hepatitis C virus: Higher prevalence of KIR 2DL3 and KIR 2DS4 and a possible role of the B haplotype? Results of a pilot prevalence study from the Mediterranean area

Hoteit, Rouba M.; Ibrahim, Georges Y.; Shammaa, Dina M.R.; Mahfouz, Rami A.R. (Elsevier Inc, 2016)

Introduction Hepatitis C virus (HCV) is a common chronic infection worldwide affecting approximately 170 million people. 80% of acutely infected people fail to eliminate the virus and develop into the chronic phase. Some ...
KIR genotype distribution among patients with multiple myeloma: Higher prevalence of KIR 2DS4 and KIR 2DS5 genes

Hoteit, Rouba M.; Bazarbachi, Ali Abdul Hamid; Antar, Ahmad I.; Salem, Ziad M.; Shammaa, Dina M.R.; Mahfouz, Rami A.R. (Elsevier B.V., 2014)

Introduction: Natural killer (NK) cells possess an antitumor activity against multiple myeloma cells proven by the susceptibility of plasmocytes to NK lysis. In the early stage of MM, the killing of MM cells is mediated ...
KIR genotype distribution among symptomatic patients with and without Helicobacter pylori infection: Is there any role for the B haplotype?

Mahfouz, Rami A.R.; Hoteit, Rouba M.; El Hajj, Nady; Shammaa, Dina M.R.; Sharara, Ala I. (BMJ Publishing Group, 2015)

Contact of peripheral blood lymphocytes with Helicobacter pylori was proved to induce non- major histocompatibility complex-restricted cytotoxicity and natural killer cells are thought to play an important role in the ...
Lack of expression of ALK and CD30 in breast carcinoma by immunohistochemistry irrespective of tumor characteristics

Nassif, Samer R.; El-Zaatari, Ziad M.; Attieh, Michel; Hijazi, Maya M.; Fakhreddin, Najla; Aridi, Tarek; Boulos, Fouad I.; Ding, Jianxun (Lippincott Williams and Wilkins, 2019)

CD30 is a member of the tumor necrosis factor family of cell surface receptors normally expressed in lymphocytes, as well as some lymphomas, but has been described in other malignancies. Anaplastic lymphoma kinase (ALK) ...
Large esophageal schwannoma: En-bloc resection with primary closure by esophagoplasty

Degheili, Jad A.; Sfeir, Pierre M.; Khalifeh, Ibrahim M.; Hallal, Ali H. (Elsevier Ltd, 2019)

Background: Gastrointestinal schwannomas are submucosal tumors accounting for 2–7% of mesenchymal gastro-intestinal neoplasms; the stomach being the most common site. Esophageal schwannomas are more frequent in women, and ...
Large Tick (Ixodes) Infestation of the Upper Eyelid Presenting as Eyelid Mass and Preseptal Cellulitis

Jaroudi, Mahmoud O.; Mansour, Ahmad Mohammed Farid Mahmoud; Ma'Luf, Riad N.; Meduri, Alessandro; Tawil, Ayman N.; Younis, Muhammad H. (S. Karger AG, 2019)

A child was referred for removal of an eyelid mass. She had preseptal cellulitis and a large tick deeply embedded in the tarsus of the upper eyelid necessitating antibiotic therapy and en-bloc excision of the tick with the ...
Late antibody-mediated rejection in a kidney transplant recipient: COVID 19 induced?

Nourie, Nicole; Nassereddine, Hussein; Mouawad, Sarah; Chebbou, Louaa; Ghaleb, Rita; Abbas, Fatmeh Ibrahim; Azar, Hiba (BioMed Central Ltd, 2022)

Background: Antibody-mediated rejection (AMR) was described in kidney transplant patients after viral infections, such as the cytomegalovirus. Very few cases were recently reported after severe acute respiratory syndrome ...
Lenalidomide in combination with arsenic trioxide: An effective therapy for primary effusion lymphoma

Moodad, Sara; El Hajj, Rana H.; Hleihel, Rita S.; El-Hajjar, Layal; Tawil, Nadim M.; Karam, Martin M.; Hamie, Maguy H.; Abou-Merhi, Raghida; El-Sabban, Marwan E.; El-Hajj, Hiba Ahmad (MDPI AG, 2020)

Primary effusion lymphoma (PEL) is a rare aggressive subset of non-Hodgkin B cell lymphoma. PEL is secondary to Kaposi sarcoma herpes virus (KSHV) and predominantly develops in serous cavities. Conventional chemotherapy ...
Length-weight relationships and relative condition factor of fish inhabiting the marine area of the Eastern Mediterranean city, Tripoli-Lebanon

Jisr, Nazek; Younes, Ghassan O.; Sukhn, Carol M.S.; El-Dakdouki, Mohammad H. (National Institute of Oceanography and Fisheries, 2018)

Length-weight relationships (LWRs) and relative condition factor are of great importance in fishery assessment studies since it provide information about the growth of the fish, its general wellbeing, and fitness in a ...
Levels of heavy metals, total petroleum hydrocarbons, and microbial load in commercially valuable fish from the marine area of Tripoli, Lebanon

Jisr, Nazek; Younes, Ghassan O.; El-Omari, Khaled; Hamzé, Monzer M.; Sukhn, Carol M.S.; El-Dakdouki, Mohammad H. (Springer Science and Business Media Deutschland GmbH, 2020)

The present study aimed at evaluating the levels of microbiological contamination, total petroleum hydrocarbons (TPHs), and heavy metals (As, Cd, Hg, and Pb) in the edible tissues of commonly consumed fish (8 species) ...
Limitations of platform assays to measure serum 25OHD level impact on guidelines and practice decision making

Rahme, Maya; Al-Shaar, Laila; Singh, Ravinder Jit; Baddoura, Rafic M.; Halaby, Georges H.; Arabi, Asma; Habib, Robert H.; Daher, Rose T.; Bassil, Darina; El-Ferkh, Karim; Hoteit, M.; El-Hajj Fuleihan, Ghada A. (W.B. Saunders, 2018)

Context: Liquid Chromatography Mass Spectroscopy (LC-MS/MS) is the preferred method to measure 25 hydroxyvitamin D (25OHD) levels, but laboratories are increasingly adopting automated platform assays. Objective: We assessed ...
Linezolid toxicity and mitochondrial susceptibility: A novel neurological complication in a lebanese patient

Abou-Hassan, Ossama K.; Karnib, Mohamad; El-Khoury, Riyad; Nemer, Georges M.; Barmada, Mamdouha Abdab; Bou-Khalil, Pierre (Frontiers Media S.A., 2016)

The recent rise in the use of linezolid to treat a variety of resistant pathogens has uncovered many side effects. Some patients develop lactic acidosis, myelosuppression, optic or peripheral neuropathies, and myopathies. ...
Liver resection for metastatic colorectal leiomyosarcoma: A single center experience

Faraj, Walid G.; El-Kehdy, Jessica; Nounou, Ghina El; Deeba, Samer; Fakih, Hawraa; Jabbour, Mark N.; Haydar, Ali A.; Naaj, Abdallah Abou El; Abou-Alfa, Ghassan Khaled; O'Reilly, Eileen Mary; Shamseddine, Ali I.; Khalife, Mohamad Jawad; Mukherji, Deborah M. (Pioneer Bioscience Publishing, 2015)

Background: Leiomyosarcoma arising in the colorectum is a rare malignancy of the smooth muscles accounting for less than 1% of gastrointestinal tumors. Surgery remains the most accepted modality for the treatment of this ...
Loss of interleukin-10 activates innate immunity to eradicate adult T-cell leukemia-initiating cells

El-Hajj, Hiba Ahmad; Hleihel, Rita S.; El-Sabban, Marwan E.; Bruneau, Julie; Zaatari, Ghazi S.; Cheminant, Morgane; Marçais, Ambroise; Akkouche, Abdou; Hasegawa, Hideaki; Hall, William W.; de Thȩ, Hugues B.; Hermine, Olivier; Bazarbachi, Ali Abdul Hamid (Ferrata Storti Foundation, 2021)

Adult T-cell leukemia/lymphoma (ATL) is associated with chronic human T-cell leukemia virus type 1 infection and carries a poor prognosis. Arsenic trioxide (AS) and interferon-alpha (IFNα) together selectively trigger Tax ...
Loss of KLK4::KLKP1 pseudogene expression by RNA chromogenic in-situ hybridization is associated with PTEN loss and increased risk of biochemical recurrence in a cohort of middle eastern men with prostate cancer

Bakker, Andrea C.; Slack, Jonathan C.; Palanisamy, Nallasivam; Carskadon, Shannon L.; Ghosh, Sunita S.; Khalifeh, Ibrahim M.; Bismar, Tarek A. (Springer Science and Business Media Deutschland GmbH, 2023)

Background: KLK4::KLKP1 fusion is a recently described pseudogene that is enriched in prostate cancer (PCa). This new biomarker has not been characterized in the Middle Eastern population. Objective: To establish the ...

Now showing items 197-216 of 389

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Browsing Pathology and Laboratory Medicine by Title

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