• Trends in epidemiology and management of breast cancer in developing Arab countries: A literature and registry analysis 

  El Saghir N.S.; Khalil M.K.; Eid T.; El Kinge A.R.; Charafeddine M.; Geara F.; Seoud M.; Shamseddine A.I. (, 2007)

  Background: Registries and research on breast cancer in Arabic and developing countries are limited. Methods: We searched PubMed, Medline, WHO and IAEA publications, national, regional, hospital tumor registries and ...
• Effects of young age at presentation on survival in breast cancer 

  El Saghir N.S.; Seoud M.; Khalil M.K.; Charafeddine M.; Salem Z.K.; Geara F.B.; Shamseddine A.I. (LONDONMIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON W1T 4LB, ENGLAND, 2006)

  Background: Young age remains a controversial issue as a prognostic factor in breast cancer. Debate includes patients from different parts of the world. Almost 50percent of patients with breast cancer seen at the American ...
• Spectral reconstruction by scatter analysis for a linear accelerator photon beam 

  Jalbout W.T.; Spyrou N.M. (BRISTOLDIRAC HOUSE, TEMPLE BACK, BRISTOL BS1 6BE, ENGLAND, 2006)

  Pre-existing methods for photon beam spectral reconstruction are briefly reviewed. An alternative reconstruction method by scatter analysis for linear accelerators is introduced. The method consists in irradiating a small ...
• Edmond-Philippe Malaise (1930-2013): a lifetime of perseverance leads to the cellular definition of intrinsic radiosensitivity. 

  Foray N.; Badie C.; Alsbeih G.; Lambin P.; Geara F.; Taghian A.G.; Deschavanne P.; Gueulette J.; Courdi A.; Chavaudra N.; Fertil B. (, 2014)

  [No abstract available]
• A comparative study on the risks of radiogenic second cancers and cardiac mortality in a set of pediatric medulloblastoma patients treated with photon or proton craniospinal irradiation 

  Zhang R.; Howell R.M.; Taddei P.J.; Giebeler A.; Mahajan A.; Newhauser W.D. (CLAREELSEVIER HOUSE, BROOKVALE PLAZA, EAST PARK SHANNON, CO, CLARE, 00000, IRELAND, 2014)

  Purpose: To compare the risks of radiogenic second cancers and cardiac mortality in 17 pediatric medulloblastoma patients treated with passively scattered proton or field-in-field photon craniospinal irradiation (CSI). ...
• Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells 

  Itani W.; Geara F.; Haykal J.; Haddadin M.; Gali-Muhtasib H. (LONDON236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND, 2007)

  Background: The sensitizing effects of 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide (DCQ) and ionizing radiation (IR) were determined in four colon cancer cells and in FHs74Int normal intestinal cells. Methods: ...
• Nasopharyngeal cancer in the Middle East: Experience of the American University of Beirut Medical Center 

  Geara F.B.; Nasr E.; Tucker S.L.; Brihi E.; Zaytoun G.; Hadi U.; Salem Z.; El Saghir N.; Issa P.; Shamseddine A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2005)

  Purpose: To review the data of nasopharyngeal carcinoma (NPC) treated at the American University of Beirut Medical Center and reflect on the characteristics and treatment outcome of NPC in the Middle East compared with ...
• Duodenal mucosa-associated lymphoid tissue lymphoma successfully treated by radiation therapy 

  Azar C.; Soweid A.; Berro Z.; Salem Z.M.K.; Geara F.B.; Kattar M.M.; Hashash J.G.; Barada K.A. (DALLAS3500 MAPLE AVENUE, STE 750, DALLAS, TX 75219-3931 USA, 2007)

  Duodenal mucosa-associated lymphoid tissue (MALT) lymphoma is very rare, and little is known about its clinical characteristics, endoscopic and endosonographic features, and treatment. We hereby report a case of duodenal ...
• Cyclophosphamide and topotecan as first-line salvage therapy in patients with relapsed ewing sarcoma at a single institution 

  Farhat R.; Raad R.; Khoury N.J.; Feghaly J.; Eid T.; Muwakkit S.; Abboud M.; El-Solh H.; Saab R. (PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2013)

  The combination of cyclophosphamide and topotecan (cyclo-topo) has shown objective responses in relapsed Ewing sarcoma, but the response duration is not well documented. We reviewed characteristics and outcome of 14 patients ...
• Rhabdomyosarcoma treatment and outcome at a multidisciplinary pediatric cancer center in Lebanon 

  Salman M.; Tamim H.; Medlej F.; El-Ariss T.; Saad F.; Boulos F.; Eid T.; Muwakkit S.; Khoury N.; Abboud M.; Saab R. (LONDONTELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2012)

  Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Outcome of patients treated on standard protocols, in a multidisciplinary cancer center setting outside of clinical trials, is not well reported. ...
• Fight against cancer around the Mediterranean area: Many hands make light work! 

  Belkacemi Y.; Boussen H.; Turkan S.; Tsoutsou P.G.; Geara F.; Gligorov J. (, 2012)

  The geopolitical and strategic importance of the Mediterranean area is evident since a long time. In terms of health programs and means for cancer care, significant disparities have been reported between countries that ...
• Trauma-associated growth of suspected dormant micrometastasis 

  El Saghir N.S.; Elhajj I.I.; Geara F.B.; Hourani M.H. (LONDONMIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON W1T 4LB, ENGLAND, 2005)

  Background: Cancer patients may harbor micrometastases that remain dormant, clinically undetectable during a variable period of time. A traumatic event or surgery may trigger the balance towards tumor growth as a result ...
• Primary spontaneous pneumothorax, an era of fresh air 

  Chebl R.B.; Noujeim C.; Ayoub Z.; Dagher G.A. (, 2013)

  Background: There are no rigid guidelines for the management of primary spontaneous pneumothorax. Although there seems to be a consensus between several medical societies regarding the management of an asymptomatic small ...
• Predicted risks of radiogenic cardiac toxicity in two pediatric patients undergoing photon or proton radiotherapy 

  Zhang R.; Howell R.M.; Homann K.; Giebeler A.; Taddei P.J.; Mahajan A.; Newhauser W.D. (LONDON236 GRAYS INN RD, FLOOR 6, LONDON WC1X 8HL, ENGLAND, 2013)

  Background: Hodgkin disease (HD) and medulloblastoma (MB) are common malignancies found in children and young adults, and radiotherapy is part of the standard treatment. It was reported that these patients who received ...
• The predicted relative risk of premature ovarian failure for three radiotherapy modalities in a girl receiving craniospinal irradiation 

  Perez-Andujar A.; Newhauser W.D.; Taddei P.J.; Mahajan A.; Howell R.M. (BRISTOLTEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND, 2013)

  In girls and young women, irradiation of the ovaries can reduce the number of viable ovarian primordial follicles, which may lead to premature ovarian failure (POF) and subsequently to sterility. One strategy to minimize ...
• A reduced intensity conditioning regimen of fludarabine, cyclophosphamide, antithymocyte globulin, plus 2 Gy TBI facilitates successful hematopoietic cell engraftment in an adult with dyskeratosis congenita 

  Kharfan-Dabaja M.A.; Otrock Z.K.; Bacigalupo A.; Mahfouz R.A.; Geara F.; Bazarbachi A. (LONDONMACMILLAN BUILDING, 4 CRINAN ST, LONDON N1 9XW, ENGLAND, 2012)

  [No abstract available]
• Analytical model for out-of-field dose in photon craniospinal irradiation 

  Taddei P.J.; Jalbout W.; Howell R.M.; Khater N.; Geara F.; Homann K.; Newhauser W.D. (BRISTOLTEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND, 2013)

  The prediction of late effects after radiotherapy in organs outside a treatment field requires accurate estimations of out-of-field dose. However, out-of-field dose is not calculated accurately by commercial treatment ...
• Outcome of breast cancer patients treated outside of clinical trials 

  El Saghir N.S.; Assi H.A.; Jaber S.M.; Khoury K.E.; Nachef Z.; Mikdashi H.F.; El-Asmar N.S.; Eid T.A. (Ivyspring International Publisher; LAKE HAVENPO BOX 4546, LAKE HAVEN, NSW 2263, AUSTRALIA, 2014)

  Background: Information on outcome of breast cancer patients treated in the community is scarce. Data on outcome of patients treated in real-life clinical practice may provide useful information for performance improvement. ...
• Comparison of risk of radiogenic second cancer following photon and proton craniospinal irradiation for a pediatric medulloblastoma patient 

  Zhang R.; Howell R.M.; Giebeler A.; Taddei P.J.; Mahajan A.; Newhauser W.D. (BRISTOLTEMPLE CIRCUS, TEMPLE WAY, BRISTOL BS1 6BE, ENGLAND, 2013)

  Pediatric patients who received radiation therapy are at risk of developing side effects such as radiogenic second cancer. We compared proton and photon therapies in terms of the predicted risk of second cancers for a 4 ...
• The radiosensitizer 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide induces DNA damage in EMT-6 mammary carcinoma cells 

  Haykal J.; Geara F.; Haddadin M.J.; Smith C.A.; Gali-Muhtasib H. (LONDONCURRENT SCIENCE GROUP, MIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON W1T 4LB, ENGLAND, 2009)

  Background: DCQ (2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide), a synthetic quinoxaline 1,4-dioxide, enhances the cytotoxic effect of ionizing radiation (IR) in vivo and in vitro. We sought to clarify whether ...

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