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Office of the VP for Medical Affairs - Faculty Publications

Office of the VP for Medical Affairs - Faculty Publications

 

Recent Submissions

  • Akl E.A.; Maroun N.; Major S.; Afif C.; Chahoud B.; Choucair J.; Sakr M.; Schunemann H.J. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, ENGLAND, 2007)
    In the context of a worldwide physician brain drain phenomenon, Lebanon has the highest emigration factor in the Middle East and North Africa. In this manuscript we aim to identify and develop a conceptual framework for ...
  • Fawaz A.; Badr K.F. (PHILADELPHIA530 WALNUT ST, PHILADELPHIA, PA 19106-3621 USA, 2006)
    PURPOSE OF REVIEW: The global prevalence of chronic kidney disease is increasing, as are its complications. Central to the diagnosis, evaluation and management of chronic kidney disease is the estimation of glomerular ...
  • Akl E.A.; Maroun N.; Major S.; Chahoud B.; Schunemann H.J. (LONDONMIDDLESEX HOUSE, 34-42 CLEVELAND ST, LONDON W1T 4LB, ENGLAND, 2007)
    Background. As healthcare systems around the world are facing increasing physician shortages, more physicians are migrating from low to high income countries. As an illustrative case of international migration of physicians, ...
  • Kearon C.; Akl E.A. (American Society of Hematology; WASHINGTON2021 L ST NW, SUITE 900, WASHINGTON, DC 20036 USA, 2014)
    It takes about 3 months to complete active treatment of venous thromboembolism (VTE), with further treatment serving to prevent new episodes of thrombosis (pure secondary prevention). Consequently, VTE should generally be ...
  • Kristiansen A.; Brandt L.; Agoritsas T.; Akl E.A.; Berge E.; Bondi J.; Dahm A.E.; Granan L.-P.; Halvorsen S.; Holme P.-A.; Jacobsen A.F.; Jacobsen E.-M.; Neumann I.; Sandset P.M.; Saetre T.; Tveit A.; Vartdal T.; Guyatt G.; Vandvik P.O. (American College of Chest Physicians; GLENVIEW2595 PATRIOT BLVD, GLENVIEW, IL 60026 USA, 2014)
    BACKGROUND: Adaptation of guidelines for use at the national or local level can facilitate their implementation. We developed and evaluated an adaptation process in adherence with standards for trustworthy guidelines and ...
  • Akl E.A.; Guyatt G.H. (American College of Physicians;, 2014)
    [No abstract available]
  • Symons A.B.; Morley C.P.; McGuigan D.; Akl E.A. (NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2014)
    Background Early, frequent encounters with people with disabilities may improve medical students' knowledge, attitudes and skills regarding their care. We developed and implemented a longitudinal four-year curriculum ...
  • Badr K. (NEW YORK75 VARICK STREET, 9TH FLOOR, NEW YORK, NY 10013-1917 USA, 2006)
    [No abstract available]
  • Badr K.F.; Abi-Antoun T.E. (LARCHMONT2 MADISON AVENUE, LARCHMONT, NY 10538 USA, 2005)
    Isoprostanes are not mere bystanders of oxidative injury, but possess potent biological activity and may thus contribute to the pathophysiology of various disorders associated with an increase in free radical formation. ...
  • Ebrahim S.; Johnston B.C.; Akl E.A.; Mustafa R.A.; Sun X.; Walter S.D.; Heels-Ansdell D.; Alonso-Coello P.; Guyatt G.H. (Elsevier USA; NEW YORK360 PARK AVE SOUTH, NEW YORK, NY 10010-1710 USA, 2014)
    Background We previously developed an approach to address the impact of missing participant data in meta-analyses of continuous variables in trials that used the same measurement instrument. We extend this approach to ...
  • Kasenda B.; Von Elm E.; You J.; Blumle A.; Tomonaga Y.; Saccilotto R.; Amstutz A.; Bengough T.; Meerpohl J.J.; Stegert M.; Tikkinen K.A.O.; Neumann I.; Carrasco-Labra A.; Faulhaber M.; Mulla S.M.; Mertz D.; Akl E.A.; Bassler D.; Busse J.W.; Ferreira-Gonza (American Medical Association; CHICAGO330 N WABASH AVE, STE 39300, CHICAGO, IL 60611-5885 USA, 2014)
    IMPORTANCE: The discontinuation of randomized clinical trials (RCTs) raises ethical concerns and often wastes scarce research resources. The epidemiology of discontinued RCTs, however, remains unclear. OBJECTIVES To determine ...
  • Fiorina P.; Vergani A.; Bassi R.; Niewczas M.A.; Altintas M.M.; Pezzolesi M.G.; D'Addio F.; Chin M.; Tezza S.; Ben Nasr M.; Mattinzoli D.; Ikehata M.; Corradi D.; Schumacher V.; Buvall L.; Yu C.C.; Chang J.M.; La Rosa S.; Finzi G.; Solini A.; Vincenti F.; (WASHINGTON1725 I ST, NW STE 510, WASHINGTON, DC 20006 USA, 2014)
    Podocyte injury and resulting albuminuria are hallmarks of diabetic nephropathy, but targeted therapies to halt or prevent these complications are currently not available. Here, we show that the immune-related molecule ...
  • Azzi J.R.; Sayegh M.H.; Mallat S.G. (BETHESDA9650 ROCKVILLE PIKE, BETHESDA, MD 20814 USA, 2013)
    Calcineurin inhibitors (CNIs) revolutionized the field of organ transplantation and remain the standard of care 40 years after the discovery of cyclosporine. The early impressive results of cyclosporine in kidney transplant ...
  • Badr K.F. (OXFORD9600 GARSINGTON RD, OXFORD OX4 2DQ, OXON, ENGLAND, 2005)
    [No abstract available]
  • Akl E.A.; Guyatt G. (2013)
    [No abstract available]
  • Riella L.V.; Sayegh M.H. (LONDONTELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2013)
    Introduction: The concern about nephrotoxicity with calcineurin inhibitors led to the search of novel agents for immunosuppression. Based on the requirement of T-cell co-stimulatory signals to fully activated naïve T cells, ...
  • Yeung M.Y.; Najafian N.; Sayegh M.H. (LONDONTELEPHONE HOUSE, 69-77 PAUL STREET, LONDON EC2A 4LQ, ENGLAND, 2014)
    Introduction: The pivotal role of costimulatory pathways in regulating T-cell activation versus tolerance has stimulated tremendous interest in their manipulation for therapeutic purposes. Of these, the CD28-B7 pathway is ...
  • Response 
    Falck-Ytter Y.; Kearon C.; Akl E.; Francis C. (2013)
    [No abstract available]
  • Schunemann H.J.; Wiercioch W.; Etxeandia I.; Falavigna M.; Santesso N.; Mustafa R.; Ventresca M.; Brignardello-Petersen R.; Laisaar K.-T.; Kowalski S.; Baldeh T.; Zhang Y.; Raid U.; Neumann I.; Norris S.L.; Thornton J.; Harbour R.; Treweek S.; Guyatt G.; (OTTAWA1867 ALTA VISTA DR, OTTAWA, ONTARIO K1G 5W8, CANADA, 2014)
    Background: Although several tools to evaluate the credibility of health care guidelines exist, guidance on practical steps for developing guidelines is lacking. We systematically compiled a comprehensive checklist of items ...
  • Alam S.E.; Nasser S.; Fernainy K.E.; Habib A.A.; Badr K.F. (OXFORDTHE BOULEVARD, LANGFORD LANE, KIDLINGTON, OXFORD OX5 1GB, OXON, ENGLAND, 2004)
    The excessive mortality of coronary heart disease is attributed primarily to rupture and thrombotic transformation of the atherosclerotic plaque. Inflammation plays a critical role in plaque destabilization and vulnerability. ...

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