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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Anatomy, Cell Biology, and Physiological Sciences"

Now showing items 1-20 of 53

Adiponectin attenuates cyclophilin A induced vascular remodeling in response to mechanical stretch and angiotensin-II -

Radwan, Zeina Ali (2017)

Obesity is among the world major public health problems. It is associated with cardiovascular diseases (CVD) including hypertension and other comorbid conditions. However, the mechanisms that contribute to the development ...
Anti-tumor Effect of the Adamantyl Retinoid ST1926 in Combination with 5-Fluorouracil in Pancreatic Cancer

Beqai, Wafaa Toufic (4/22/2021)

Pancreatic cancer is considered as one of the most fatal malignancies, ranking as the seventh leading cause of worldwide cancer-related deaths in industrialized countries and the third most common in the U.S.A. Despite ...
Assessing the anti-cancer activities of novel therapeutics on human Medulloblastoma cancer cells

Mekawi, Rouba Jamal (7/6/2021)

Background: Medulloblastoma (MB) is the most common malignant intra-cranial solid tumor among children. Extensive research has been implicated in this field to look for novel therapeutic options that could help alleviate ...
Assessing the Radioprotecting Effect of ZoPra on Human Prostate Epithelial Cells and Human Fibroblast Cells.

Fawaz, Jhonny (9/16/2022)

Prostate cancer is the most prevalent cancer in men and the second leading cause of cancer-related deaths in men around the world. One of the first-line treatments for lowering tumor size and preventing further cancer ...
Autologous Fat Promotes Second Degree Burn Wound Healing in Diabetic Rats: A Mechanistic Approach

Hijal, Nora (5/10/2021)

Introduction: Adipocytes have several roles in different tissues that go beyond simple energy storage to include metabolism regulation and growth. There is evidence that adipocytes have immunological and stem cells like ...
Characterization of post-traumatic epileptiform features and behavioral disturbances in a clinically-relevant rodent model of hemorrhagic closed-head injury

Jalloul, Dounya Fouad (2019)

Background: Currently, there are no clinically available treatments to prevent traumatic brain injury (TBI)-related epilepsy, and the associated cognitive disturbances. Post-traumatic epilepsy (PTE) represents 20percent ...
Depression Induced by Early-life Hypoxic Seizures: Pathogenesis and Molecular Alterations

El Serghani, Marie-Michele (9/14/2021)

Background: Children with epilepsy are more likely to develop depression which reduces their quality of life and leads to higher suicide risks in adolescence. The treatment of depression that accompanies epilepsy is ...
Dimorphism In The Association Between Diabetes And Depression: Unraveling Novel Biological Perspectives

Saad, Celine Georges (9/23/2020)

Background: Diabetes and depression are two disorders that are among the leading non-communicable diseases currently on the horizon worldwide. Recent epidemiological studies highlight the rising occurrence of depression ...
The Effect of Ciprofloxacin on Sensory Processing, Cognition, and Hippocampal Neurogenesis in Healthy Rats

Naddour, Judith (9/15/2022)

Ciprofloxacin (CPFX), a broad-spectrum antibiotic in the fluoroquinolone class, is one of the most widely prescribed agents for uncomplicated cases of urinary tract infections (UTI). However, over the past decade, the ...
Effect of Cyclophilin "A" and Cyclosporine "A" on DSS-Induced IBD in Syndecan-1 Knock out Mice in Presence and Absence of Probiotics

Lezeik, Roaa (12/20/2022)

Introduction: Inflammatory Bowel Disease (IBD) is a chronic relapsing autoimmune inflammatory disease that results from the interplay between genetic and environmental factors. Cyclosporine “A” (CysA) has been described ...
THE EFFECT OF NON-CONVULSIVE SEIZURE BURDEN ON COGNITION AND EMOTIONAL BEHAVIOR IN PERI-ADOLESCENT RATS

El Ayoubi, Nour (9/15/2022)

Background: Non-Convulsive status epilepticus (NCSE) consists of prolonged seizures without tonic muscle stiffening or clonic rhythmic activity. In a clinical setting, NCSE is often underdiagnosed due to difficulties in ...
Effect of the Immunomodulatory Drug EAP0503 on Mutant Nucleophosmin-1 Function in Acute Myeloid Leukemia

Jishi, Batoul Hussein (2019)

Nucleophosmin-1 mutation (NPM1c) represents one of the most frequent mutations in Acute Myeloid Leukemia (AML). In NPM1c AML, NPM-1 is aberrantly exported to the cytoplasm, contributing to leukemogenesis. Ribosomal biogenesis ...
The Effect of Vitamin D Supplementation During Pregnancy on Placental Function in Preeclampsia, Intrauterine Growth Restriction, and Preterm Birth.

Kharrat, Lea (8/18/2021)

Background: The human placenta is a transitory organ playing the role of multiple organs during pregnancy. It is composed of trophoblastic cells that respond to vitamin D. Vitamin D is a secosteroid hormone that plays an ...
Effect of Vitamin D Supplementation on mRNA Expression of Calcium Transporters, Hormones, and Receptors During Pregnancy

Elkhalil, Nadin Fadi (2/10/2023)

Introduction: Vitamin D deficiency is a common disorder worldwide. It has many risk factors and impacts on the human body. Interestingly, this hypovitaminosis is prevalent in pregnant women, and the majority of them are ...
ELECTROCONVULSIVE THERAPY FOR YOUNG MINDS: A SOLUTION FOR MENTAL DYSFUNCTION OR A PROBLEM FOR COGNITION? A SYSTEMATIC REVIEW AND META-ANALYSIS

Dabboussi, Nour (9/18/2021)

Title: Electroconvulsive Therapy For Young Minds: A Solution For Mental Dysfunction Or A Problem For Cognition? A Systematic Review And Meta-Analysis Introduction: Electroconvulsive therapy (ECT) is a medical treatment ...
Growth Differentiation Factor (GDF-15) as a Major Player in Diabetes-Induced Renal and Cardiovascular Injuries: A Mechanistic Approach

Noureddine, Maya (9/12/2022)

Introduction: Diabetes, being a major cause of morbidity worldwide, can simultaneously cause renal (Diabetic Kidney Disease) and cardiac dysfunction. Recent data suggest that in the presence of tissue injury, inflammation, ...
Growth Differentiation Factor-15 (GDF-15) and Inflammation in Diabetic Kidney Disease: A Friend, A Foe, Or A Fellow Traveler.

Sfeir, Ghiwa (2023-08-23)

Introduction: Diabetes Mellitus is associated with several complications, among which is diabetic kidney disease (DKD). DKD is considered the strongest predictor of mortality in diabetic patients and the main cause of ...
HOW SAFE IS GADOBUTROL? EXAMINING THE EFFECT OF GADOLINIUM DEPOSITION ON THE NERVOUS SYSTEM

Jammoul, Maya (9/17/2021)

Background and objective: Repeated administration of Gadolinium based contrast agents (GBCAs) has been shown to cause Gadolinium (Gd) deposition in the nervous system. It is unclear whether neurotoxic effects can arise ...
Identifying Novel Mechanistic Pathways Underlying Pathogenesis of Endometriosis

Assaf, Lama (1/25/2022)

Background: Endometriosis is the growth of endometrial tissue outside the uterine cavity usually in the ovaries, fallopian tube, and the pelvic cavity. It affects 1 in 10 women which is approximately 176 million women ...
Investigating the Antineoplastic Effect of NSAIDs (Piroxicam) and Statins (Atorvastatin) on Prostate Cancer: Novel Therapeutic Potential

Abdul Samad, Tamara (5/16/2022)

Prostate cancer (PCa) is currently a challenging medical health issue worldwide. For the last 30+ years, PCa has been the most common cancer among men. Mortality due to metastatic castration-resistant PCa (CRPC) becomes ...

Now showing items 1-20 of 53

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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Anatomy, Cell Biology, and Physiological Sciences"

Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Anatomy, Cell Biology, and Physiological Sciences"

Search AUB ScholarWorks

Browse

All of AUB ScholarWorks

This Collection

My Account

Copyright Statement