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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Experimental Pathology, Immunology, and Microbiology"

Now showing items 1-20 of 33

Assessment and Characterization of an Anti-EBV Compound Extracted from Soil-Dwelling Bacteria

Saadeh, Marwan (9/6/2022)

Introduction: The Epstein Barr Virus (EBV) is thought to infect >90% of the population world-wide; the virus then establishes latency in resting memory B-cells. The virus is associated with infectious mononucleosis (IM), ...
CARBAPENEMASES, THEIR INHIBITORS, AND PERSISTER CELLS IN MDR AND XDR GRAM-NEGATIVE BACTERIA AT AUBMC

Banna, Hanin (7/26/2021)

Background: Antimicrobial resistance is posing an increasing risk to public health due to the overuse, abuse and miss-use of the available agents, especially with multi-drug resistant (MDR) and extensive-drug resistant ...
Characterization of UTI causing E.coli and K.pneumoniae clinical isolates and assessing their effect on urinary tract cells

Abdel Khalek, Pascal (9/8/2021)

Title: Characterization of UTI Causing E.coli and K.pneumoniae Clinical Isolates and Assessing their Effect on Urinary Tract Cells Background: Urinary tract infections are among the most common bacterial infections in ...
The Contribution of Two Mutations in STX11 and LCP2 to the Disease in a Patient with an Inborn Error of Immunity

El-Hassan, Rana (4/20/2022)

Inborn Errors of Immunity (IEI) or Primary Immunodeficiencies Diseases (PIDs) comprise 406 disorders originating from 430 defected genes recorded to date. While generally monogenic, mounting evidence suggests the contribution ...
DEVELOPMENT OF A LONG-LASTING HUMORAL IMMUNE RESPONSE AGAINST THE Pfizer/BioNTech mRNA-BASED VACCINE IN HEALTHY ADULT PARTICIPANTS

El Masri, Sara (5/16/2022)

In December 2019, a cluster of pneumonia cases of unknown etiology was reported in Wuhan City, China. Later, the causative agent was identified as a new member of coronaviruses, and was named SARS-CoV-2. This virus quickly ...
Discovery of Novel Antibacterial Agents Targeting MRSA Pathogens from Unexploited Actinomycetes

Yammine, Christelle Kamal (9/23/2020)

Background: Antimicrobial resistance (AMR) has been present ever since the discovery of the first classes of antibiotics, where Sir Alexander Fleming warned about it in his Nobel Prize speech back in 1945. With the lack ...
EAPB0503 targets toll-like receptors in acute myeloid leukemia with mutated nucleophosmin-1

Skayneh, Hala Ali (2019)

Background: Acute myeloid leukemia (AML) is one of the most frequent and heterogeneous hematological malignancies in adults. Despite the advances in the understanding and treatment of AML, this leukemia still associates ...
The Effect of EBV on Inflammatory Processes in a Type 1 Autoimmune Diabetes Mellitus Mouse Model

Obeid, Hiba (2022-05-18)

Introduction: Type 1 diabetes (T1D) is considered a complex heterogeneous autoimmune disease. It occurs due to the destruction of insulin-producing beta cells of the islets of Langerhans of the pancreas. Risk factors of ...
Effect of EBV on Inflammatory Processes in a Type 1 Diabetes Mellitus Mouse Model

Kassem, Aya (5/5/2023)

The Epstein-Barr virus (EBV), also referred to as Human herpes virus 4 (HHV-4), is a double-stranded virus that belongs to the Herpesviridae family of viruses. It is estimated that this ubiquitous virus has infected more ...
Effect of Epstein-Barr Virus DNA on the Severity of Intestinal Inflammation in a Mouse Model of Acute Colitis

Andari, Sirine Imad (9/23/2020)

Background: Epstein-Barr virus (EBV) infection has been lately associated with inflammatory bowel disease (IBD), which is a collective term for chronic relapsing inflammatory disorders of the gastrointestinal tract with a ...
Effect of Imiquimod on Chronic Toxoplasmosis and its Associated Neurological Complications in a Rat Model

Itani, Shaymaa (9/9/2022)

Background: Toxoplasma gondii (T. gondii) is the etiologic agent of toxoplasmosis, a prevalent protozoan parasitosis infecting one-third of the human population worldwide and more than two-thirds of the Lebanese population. ...
Effect of Toll-Like Receptor 7 Pathway Inhibition on the Severity of Epstein-Barr virus DNA-Exacerbated Intestinal Inflammation in a Mouse Model of Inflammatory Bowel Disease

Sabra, Hady (5/16/2022)

Background: An Epstein-Barr virus (EBV) infection was proposed to play a role in the pathogenesis of inflammatory bowel disease (IBD), a chronic inflammatory malady with a poorly defined etiology. In recent research conducted ...
Establishment of a Bacteriophages Platform: Alternative Therapeutic Option

Abdo Ahmad, Tasnime (9/1/2022)

Background: Pathogenic Escherichia coli, common water contaminant, cause a large number of morbidity and mortality worldwide. Unfortunately, unrestricted use of antibiotics led to the appearance and spread of antibiotic ...
Factors and outcomes associated with influenza virus loads in hospitalized patients

Sabra, Reem (7/26/2021)

Annual influenza outbreaks constitute a substantial economic and public health burden accounting for 3-5 million hospitalizations and up to 645 000 deaths worldwide. Two influenza A subtypes (H1N1pdm09 and H3N2) and two ...
From bugs to drugs: novel anti-microbial agents from Lebanese soil and marine dwelling microorganisms

Awada, Bassel (5/9/2023)

Antimicrobial resistance (AMR) is the phenomenon by which microorganisms become non-susceptible to their originally designed drugs. AMR became a serious public health issue, as multidrug-resistant microorganisms are ...
THE FUNCTIONAL ROLE OF DROSOPHILA MELANOGASTER TEN ELEVEN TRANSLOCATION PROTEIN dTET ON HUMORAL IMMUNITY

Jaber, Nourice (5/18/2022)

Introduction: DNA demethylation, an epigenetic mechanism mediated by Tet proteins, is commonly known to modulate gene expression. Tet proteins in mammals are involved in the development and differentiation of various cells, ...
HETEROCELLULAR INTERACTION IN ORGAN SPECIFIC METASTASIS OF PROSTATE AND BREAST CANCER CELLS TO THE BONE: EXPLORING A ROLE FOR NUCLEOPHOSMIN-1

Al Shoukari, Ayman (5/4/2023)

Background: Metastasis remains the central feature of cancer malignancy and causes most of cancer-related deaths. Organo-tropic metastasis is defined as the preference of cancer cells to colonize select distant organs from ...
Identification of Anti-Epstein-Barr Virus Compounds in Extracts from Soil-dwelling Microorganisms

Shams Eddin, Marcel (5/7/2021)

Title: Identification of Anti- Epstein-Barr Virus Compounds in Extracts from Soil-dwelling Microorganisms Introduction: Epstein-Barr virus infects more than 90% of the human population and establishes latency in resting ...
Identifying Chromatin Binding Sites of Ten Eleven Translocation Protein dTet in Drosophila Melanogaster Central Nervous System

Salman, Manal (2023-09-13)

Epigenetics refers to changes in gene expression without changing the DNA sequence and it has been shown to be involved in normal development and disease. There are various mechanisms through which gene expression is ...
The Interplay Between Epstein-Barr Virus DNA and the Gut Microbiota in the Pathogenesis of Rheumatoid Arthritis in a Mouse Model

Fadlallah, Sukayna (1/20/2022)

Background: The pathogenesis of rheumatoid arthritis (RA) is not fully understood; however, risk factors including genetic predisposition and environmental challenges such as infectious agents and alterations in the gut ...

Now showing items 1-20 of 33

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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Experimental Pathology, Immunology, and Microbiology"

Browsing AUB Students' Theses, Dissertations, and Projects by Author "Department of Experimental Pathology, Immunology, and Microbiology"

Search AUB ScholarWorks

Browse

All of AUB ScholarWorks

This Collection

My Account

Copyright Statement