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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Usta, Julnar"

Now showing items 1-15 of 15

Effect of FTY720P on lipid accumulation in HEPG2 cells

Rida, Reem (2023-09-07)

The prevalence of nonalcoholic fatty liver disease (NAFLD) is on the rise. It is characterized by an increase in hepatic lipid accumulation due to an impaired lipid metabolism. A correlation has been found lately between ...
HIGH FAT DIET MODULATES NEUROPATHOLOGICAL, METABOLIC, AND CARDIOVASCULAR ALTERATIONS IN AN EXPERIMENTAL MODEL OF TRAUMATIC BRAIN INJURY

Ibeh, Stanley (11/23/2021)

Traumatic brain injury (TBI) constitutes a major public health concern in different countries and is one of the major causes of death globally. It has been established that even though TBI occurs in the brain, it can exert ...
Inhibiting the Pentose Phosphate Pathway in Colorectal Cancer: Mannose and 5-Fluorouracil Combination Treatment

Al Hadeethi, Sadaf (8/30/2022)
INTERACTION OF ARTIFICIAL-INTRINSICALLY DISORDERED PROTEIN POLYMERS WITH ENZYME-LOADED GIANT UNILAMELLAR VESICLES

Alam, Ramy (2024-01-29)

Membrane-less organelles (MLOs) are dynamic sub-cellular compartments that form primarily via the liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs). IDPs are necessary for the reconstitution ...
Mechanisms in the Acceleration of the Regression of Liver Injury in Chronic Liver Fibrosis in Mice

Imad, Noor (5/18/2022)

Background: Sustained chronic liver injury originating from several factors including viral infection, alcohol consumption, and hepatitis may lead to hepatic fibrosis characterized by an imbalance between extracellular ...
NOVEL APPROACH FOR EX-VIVO EXPANSION OF HEMATOPOIETIC STEM CELLS USING DECELLULARIZED HUMAN UMBILICAL CORD EXTRACTS

Tamzarian, Wilson Kevork (2023-09-07)

Hematopoietic stem cell transplantations (HSCT) represent so far, the only efficient reconstructive tool for damaged bone marrow (BM) in hematological disorders. The success of these regenerative strategies relies on the ...
POSSIBLE IMPLICATIONS OF TOLL-LIKE RECEPTOR 4 (TLR4) MUTATIONS IN PATIENTS WITH NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)

Chouman, Hamsa (5/9/2023)

Title: Possible Implications of Toll-like receptor 4 mutations in patients with NonAlcoholic Fatty Liver Disease Non-Alcoholic Fatty Liver Disease (NAFLD) is defined as the accumulation of fats, mainly triglycerides, in ...
POTENTIAL HYPOCHOLESTEROLEMIC EFFECT OF MORINGA OLEIFERA LEAVES’ EXTRACT

Hassanie, Haifa (1/19/2021)

Cholesterol is a lipid component of membrane structure and a precursor of many biomolecules. Disturbance in serum cholesterol homeostasis leads to an increase in cholesterol level, that underlie cardiovascular diseases and ...
Redox State in Moringa Oleifera Treated SH-SY5Y Neuroblastoma Cell Line

Owydat, Heba (2024-05-13)

Moringa Oleifera (MO), the “Miracle Tree”, is a dietary staple that originates from India. All edible components of the tree (pods, flowers, seeds, bark, leaves) have been extensively studied and showed a richness in an ...
Statins and Alzheimer's: The Controversy on its Protective Role

Al Moussawi, Nour (9/17/2021)

Alzheimer’s disease (AD) is the most common neurodegenerative disorder affecting millions of people worldwide. It is an irreversible, untreatable disease characterized by cognitive and behavioral dysfunctions such as memory, ...
Targets Identification of the DNA Polymerase Alpha Inhibitor ST1926 in Glioblastoma: A Proteomic Approach

Ayache, Zeinab (9/7/2022)

Abstract Background: Glioblastoma multiforme (GBM) is one of the most aggressive forms of malignant brain tumors. Despite the available therapies, the median survival rate of GBM patients does not exceed two years. Tumor ...
Therapeutic Opportunities in Targeting the Pentose Phosphate Pathway in Colorectal Cancer

Ghanem, Noorhan (9/22/2020)

Introduction: Colorectal cancer (CRC) is the third most common neoplasia and the second cause of cancer-related deaths worldwide. Unlike normal cells, tumor cells deregulate their metabolism and rely on aerobic glycolysis ...
Therapeutic Targeting of the Pentose Phosphate Pathway in Colorectal Cancer Cells Using Mannose

Araji, Khaled Mohamad (9/15/2021)

Introduction: Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the second leading cause of cancer-related death worldwide. 5-Fluorouracil (5-FU) remains the first-line treatment for CRC although its ...
Therapeutic Targeting of the Pentose Phosphate Pathway in Colorectal Cancer Using 6-Aminonicotinamide and 5-Fluorouracil

Cheikh, Israa (9/8/2022)

Introduction: Despite the remarkable improvement in technology and healthcare applications, colorectal cancer (CRC) remains the third most prevalent cancer type worldwide with significant levels of mortality. 5-Fluorouracil ...
TOXICITY OF STATINS ON NEURONAL CELLS: POSSIBLE REVERSIBILITY BY MITO-Q

Sardouk, Hala (2/5/2021)

Statins are among the most commonly prescribed drugs to patients with cardiovascular events. They are cholesterol-lowering drugs that competitively inhibit HMG-CoA reductase, the rate-limiting enzyme in the mevalonate ...

Now showing items 1-15 of 15

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Browsing AUB Students' Theses, Dissertations, and Projects by Author "Usta, Julnar"

Browsing AUB Students' Theses, Dissertations, and Projects by Author "Usta, Julnar"

Search AUB ScholarWorks

Browse

All of AUB ScholarWorks

This Collection

My Account

Copyright Statement